3sbw
From Proteopedia
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| - | {{STRUCTURE_3sbw| PDB=3sbw | SCENE= }} | ||
| - | ===Crystal structure of the complex between the extracellular domains of mouse PD-1 mutant and human PD-L1=== | ||
| - | == | + | ==Crystal structure of the complex between the extracellular domains of mouse PD-1 mutant and human PD-L1== |
| - | [[ | + | <StructureSection load='3sbw' size='340' side='right'caption='[[3sbw]], [[Resolution|resolution]] 2.28Å' scene=''> |
| - | + | == Structural highlights == | |
| - | == | + | <table><tr><td colspan='2'>[[3sbw]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SBW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SBW FirstGlance]. <br> |
| - | [[3sbw]] is a 3 chain structure with sequence from [ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.28Å</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sbw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sbw OCA], [https://pdbe.org/3sbw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sbw RCSB], [https://www.ebi.ac.uk/pdbsum/3sbw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sbw ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PDCD1_MOUSE PDCD1_MOUSE] Inhibitory cell surface receptor involved in the regulation of T-cell function during immunity and tolerance. Upon ligand binding, inhibits T-cell effector functions in an antigen-specific manner. Possible cell death inducer, in association with other factors (By similarity). | ||
==See Also== | ==See Also== | ||
| - | *[[Cell death protein|Cell death protein]] | + | *[[Cell death protein 3D structures|Cell death protein 3D structures]] |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
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[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: Almo | + | [[Category: Almo SC]] |
| - | [[Category: Cao | + | [[Category: Cao E]] |
| - | [[Category: Lazar-Molnar | + | [[Category: Lazar-Molnar E]] |
| - | [[Category: Nathenson | + | [[Category: Nathenson SG]] |
| - | [[Category: Ramagopal | + | [[Category: Ramagopal UA]] |
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Current revision
Crystal structure of the complex between the extracellular domains of mouse PD-1 mutant and human PD-L1
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