2o5g
From Proteopedia
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- | [[Image:2o5g.jpg|left|200px]]<br /><applet load="2o5g" size="350" color="white" frame="true" align="right" spinBox="true" | ||
- | caption="2o5g, resolution 1.08Å" /> | ||
- | '''Calmodulin-smooth muscle light chain kinase peptide complex'''<br /> | ||
- | == | + | ==Calmodulin-smooth muscle light chain kinase peptide complex== |
- | + | <StructureSection load='2o5g' size='340' side='right'caption='[[2o5g]], [[Resolution|resolution]] 1.08Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[2o5g]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O5G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2O5G FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.08Å</td></tr> | |
- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
- | [ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2o5g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o5g OCA], [https://pdbe.org/2o5g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2o5g RCSB], [https://www.ebi.ac.uk/pdbsum/2o5g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2o5g ProSAT]</span></td></tr> |
- | + | </table> | |
- | [[ | + | == Function == |
- | + | [https://www.uniprot.org/uniprot/CALM_CHICK CALM_CHICK] Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. | |
- | + | == Evolutionary Conservation == | |
- | + | [[Image:Consurf_key_small.gif|200px|right]] | |
- | + | Check<jmol> | |
- | [ | + | <jmolCheckbox> |
- | [[ | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/o5/2o5g_consurf.spt"</scriptWhenChecked> |
- | [ | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> |
- | + | <text>to colour the structure by Evolutionary Conservation</text> | |
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2o5g ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
- | + | ==See Also== | |
+ | *[[Calmodulin 3D structures|Calmodulin 3D structures]] | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Gallus gallus]] | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Alber T]] | ||
+ | [[Category: Frederick KK]] | ||
+ | [[Category: Kranz JK]] | ||
+ | [[Category: Ng HL]] | ||
+ | [[Category: Schneeweis JK]] | ||
+ | [[Category: Valentine KG]] | ||
+ | [[Category: Wand AJ]] |
Current revision
Calmodulin-smooth muscle light chain kinase peptide complex
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Categories: Gallus gallus | Large Structures | Alber T | Frederick KK | Kranz JK | Ng HL | Schneeweis JK | Valentine KG | Wand AJ