4kiu
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Design and structural analysis of aromatic inhibitors of type II dehydroquinate dehydratase from Mycobacterium tuberculosis - compound 49d [5-[(3-nitrobenzyl)oxy]benzene-1,3-dicarboxylic acid]== | |
| + | <StructureSection load='4kiu' size='340' side='right'caption='[[4kiu]], [[Resolution|resolution]] 2.40Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4kiu]] is a 24 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KIU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KIU FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KIU:5-[(3-NITROBENZYL)OXY]BENZENE-1,3-DICARBOXYLIC+ACID'>KIU</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kiu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kiu OCA], [https://pdbe.org/4kiu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kiu RCSB], [https://www.ebi.ac.uk/pdbsum/4kiu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kiu ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/AROQ_MYCTU AROQ_MYCTU] Catalyzes a trans-dehydration via an enolate intermediate (By similarity).[HAMAP-Rule:MF_00169] | ||
| - | + | ==See Also== | |
| - | + | *[[Dehydroquinase 3D structures|Dehydroquinase 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mycobacterium tuberculosis]] | ||
| + | [[Category: Abell C]] | ||
| + | [[Category: Blundell TL]] | ||
| + | [[Category: Dias MVB]] | ||
| + | [[Category: Howard NG]] | ||
Current revision
Design and structural analysis of aromatic inhibitors of type II dehydroquinate dehydratase from Mycobacterium tuberculosis - compound 49d [5-[(3-nitrobenzyl)oxy]benzene-1,3-dicarboxylic acid]
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