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4mgj
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of cytochrome P450 2B4 F429H in complex with 4-CPI== | |
| + | <StructureSection load='4mgj' size='340' side='right'caption='[[4mgj]], [[Resolution|resolution]] 2.41Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4mgj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MGJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MGJ FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.41Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CPZ:4-(4-CHLOROPHENYL)IMIDAZOLE'>CPZ</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mgj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mgj OCA], [https://pdbe.org/4mgj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mgj RCSB], [https://www.ebi.ac.uk/pdbsum/4mgj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mgj ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CP2B4_RABIT CP2B4_RABIT] Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. In the epoxidation of arachidonic acid it has a unique preference for the 5,6-olefin. | ||
| - | + | ==See Also== | |
| - | + | *[[Cytochrome P450 3D structures|Cytochrome P450 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Oryctolagus cuniculus]] | ||
| + | [[Category: Bu W]] | ||
| + | [[Category: Im S]] | ||
| + | [[Category: Meagher J]] | ||
| + | [[Category: Rwere F]] | ||
| + | [[Category: Shaik S]] | ||
| + | [[Category: Stuckey J]] | ||
| + | [[Category: Sun C]] | ||
| + | [[Category: Tarasev M]] | ||
| + | [[Category: Usharani D]] | ||
| + | [[Category: Waskell L]] | ||
| + | [[Category: Yang Y]] | ||
| + | [[Category: Zhang H]] | ||
Current revision
Crystal structure of cytochrome P450 2B4 F429H in complex with 4-CPI
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Categories: Large Structures | Oryctolagus cuniculus | Bu W | Im S | Meagher J | Rwere F | Shaik S | Stuckey J | Sun C | Tarasev M | Usharani D | Waskell L | Yang Y | Zhang H
