4mhv
From Proteopedia
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| - | {{STRUCTURE_4mhv| PDB=4mhv | SCENE= }} | ||
| - | ===Crystal structure of the PNT domain of human ETS2=== | ||
| - | == | + | ==Crystal structure of the PNT domain of human ETS2== |
| - | [[ | + | <StructureSection load='4mhv' size='340' side='right'caption='[[4mhv]], [[Resolution|resolution]] 2.45Å' scene=''> |
| - | + | == Structural highlights == | |
| - | == | + | <table><tr><td colspan='2'>[[4mhv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MHV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MHV FirstGlance]. <br> |
| - | [[4mhv]] is a 2 chain structure with sequence from [ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mhv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mhv OCA], [https://pdbe.org/4mhv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mhv RCSB], [https://www.ebi.ac.uk/pdbsum/4mhv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mhv ProSAT]</span></td></tr> |
| - | < | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ETS2_HUMAN ETS2_HUMAN] Transcription factor activating transcription. Binds specifically the DNA GGAA/T core motif (Ets-binding site or EBS) in gene promoters and stimulates transcription.<ref>PMID:11909962</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Arrowsmith | + | [[Category: Large Structures]] |
| - | [[Category: Bountra | + | [[Category: Arrowsmith CH]] |
| - | [[Category: Burgess-brown | + | [[Category: Bountra C]] |
| - | [[Category: Cooper | + | [[Category: Burgess-brown N]] |
| - | [[Category: Edwards | + | [[Category: Cooper CDO]] |
| - | [[Category: Gileadi | + | [[Category: Edwards A]] |
| - | [[Category: Krojer | + | [[Category: Gileadi O]] |
| - | [[Category: Newman | + | [[Category: Krojer T]] |
| - | [[Category: Shrestha | + | [[Category: Newman JA]] |
| - | + | [[Category: Shrestha L]] | |
| - | + | ||
Current revision
Crystal structure of the PNT domain of human ETS2
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