4l00

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{{STRUCTURE_4l00| PDB=4l00 | SCENE= }}
 
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===Crystal structure of the apo Jak1 pseudokinase domain===
 
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{{ABSTRACT_PUBMED_24013208}}
 
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==Function==
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==Crystal structure of the apo Jak1 pseudokinase domain==
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[[http://www.uniprot.org/uniprot/JAK1_HUMAN JAK1_HUMAN]] Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor.
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<StructureSection load='4l00' size='340' side='right'caption='[[4l00]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4l00]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L00 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4L00 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4l00 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l00 OCA], [https://pdbe.org/4l00 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4l00 RCSB], [https://www.ebi.ac.uk/pdbsum/4l00 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4l00 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/JAK1_HUMAN JAK1_HUMAN] Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor.
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==About this Structure==
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==See Also==
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[[4l00]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L00 OCA].
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*[[Janus kinase 3D structures|Janus kinase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:024013208</ref><references group="xtra"/><references/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Non-specific protein-tyrosine kinase]]
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[[Category: Large Structures]]
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[[Category: Eck, M J.]]
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[[Category: Eck MJ]]
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[[Category: Toms, A V.]]
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[[Category: Toms AV]]
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[[Category: Kinase domain fold]]
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[[Category: Regulatory]]
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[[Category: Transferase]]
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Current revision

Crystal structure of the apo Jak1 pseudokinase domain

PDB ID 4l00

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