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3j4q
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3j4q is ON HOLD Authors: Reichow, S.L., Gonen, T. Description: Pseudo-atomic model of the AKAP18-PKA complex in a bent conformation derived from el...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Pseudo-atomic model of the AKAP18-PKA complex in a bent conformation derived from electron microscopy== | |
| + | <SX load='3j4q' size='340' side='right' viewer='molstar' caption='[[3j4q]], [[Resolution|resolution]] 35.00Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3j4q]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J4Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3J4Q FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 35Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3j4q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j4q OCA], [https://pdbe.org/3j4q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3j4q RCSB], [https://www.ebi.ac.uk/pdbsum/3j4q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3j4q ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/AKA7G_RAT AKA7G_RAT] Probably targets cAMP-dependent protein kinase (PKA) to the cellular membrane or cytoskeletal structures. The membrane-associated form reduces epithelial sodium channel (ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellular sodium (By similarity). Isoform Delta may be involved in shuttling aquaporin-2 (AQP2) to the plasma membrane.[UniProtKB:Q9P0M2]<ref>PMID:15037626</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[A-kinase anchor protein 3D structures|A-kinase anchor protein 3D structures]] | |
| - | + | *[[CAMP-dependent protein kinase 3D structures|CAMP-dependent protein kinase 3D structures]] | |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </SX> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Gonen T]] | ||
| + | [[Category: Reichow SL]] | ||
Current revision
Pseudo-atomic model of the AKAP18-PKA complex in a bent conformation derived from electron microscopy
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