2opg

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:46, 30 August 2023) (edit) (undo)
 
(11 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2opg.gif|left|200px]]<br /><applet load="2opg" size="350" color="white" frame="true" align="right" spinBox="true"
 
-
caption="2opg, resolution 1.50&Aring;" />
 
-
'''The crystal structure of the 10th PDZ domain of MPDZ'''<br />
 
-
==About this Structure==
+
==The crystal structure of the 10th PDZ domain of MPDZ==
-
2OPG is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NA:'>NA</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OPG OCA].
+
<StructureSection load='2opg' size='340' side='right'caption='[[2opg]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[2opg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OPG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OPG FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2opg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2opg OCA], [https://pdbe.org/2opg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2opg RCSB], [https://www.ebi.ac.uk/pdbsum/2opg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2opg ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/MPDZ_HUMAN MPDZ_HUMAN] Interacts with HTR2C and provokes its clustering at the cell surface (By similarity). Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses.<ref>PMID:11150294</ref> <ref>PMID:15312654</ref>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/op/2opg_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2opg ConSurf].
 +
<div style="clear:both"></div>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: Arrowsmith, C H.]]
+
[[Category: Arrowsmith CH]]
-
[[Category: Berridge, G.]]
+
[[Category: Berridge G]]
-
[[Category: Doyle, D A.]]
+
[[Category: Doyle DA]]
-
[[Category: Edwards, A.]]
+
[[Category: Edwards A]]
-
[[Category: Elkins, J.]]
+
[[Category: Elkins J]]
-
[[Category: Gileadi, C.]]
+
[[Category: Gileadi C]]
-
[[Category: Gileadi, O.]]
+
[[Category: Gileadi O]]
-
[[Category: Gorrec, F.]]
+
[[Category: Gorrec F]]
-
[[Category: Papagrigoriou, E.]]
+
[[Category: Papagrigoriou E]]
-
[[Category: Phillips, C.]]
+
[[Category: Phillips C]]
-
[[Category: SGC, Structural Genomics Consortium.]]
+
[[Category: Salah E]]
-
[[Category: Salah, E.]]
+
[[Category: Savitsky P]]
-
[[Category: Savitsky, P.]]
+
[[Category: Sundstrom M]]
-
[[Category: Sundstrom, M.]]
+
[[Category: Ugochukwu E]]
-
[[Category: Ugochukwu, E.]]
+
[[Category: Umeano C]]
-
[[Category: Umeano, C.]]
+
[[Category: Weigelt J]]
-
[[Category: Weigelt, J.]]
+
-
[[Category: NA]]
+
-
[[Category: sgc]]
+
-
[[Category: structural genomics]]
+
-
[[Category: structural genomics consortium]]
+
-
[[Category: structural protein]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:21:06 2008''
+

Current revision

The crystal structure of the 10th PDZ domain of MPDZ

PDB ID 2opg

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2opg"
Personal tools