4c8d
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4c8d is ON HOLD Authors: Vollmar, M., Gileadi, C., Johansson, C., Krojer, T., Crawley, L., von Delft, F., Arrowsmith, C.H., Bountra, C., Edwards, A....) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of JmjC domain of human histone 3 Lysine-specific demethylase 3B (KDM3B)== | |
| + | <StructureSection load='4c8d' size='340' side='right'caption='[[4c8d]], [[Resolution|resolution]] 2.18Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4c8d]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C8D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4C8D FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.18Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=OGA:N-OXALYLGLYCINE'>OGA</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4c8d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c8d OCA], [https://pdbe.org/4c8d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4c8d RCSB], [https://www.ebi.ac.uk/pdbsum/4c8d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4c8d ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/KDM3B_HUMAN KDM3B_HUMAN] Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity.<ref>PMID:16603237</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Jumonji domain-containing protein 3D structures|Jumonji domain-containing protein 3D structures]] | |
| - | + | == References == | |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Arrowsmith CH]] | ||
| + | [[Category: Bountra C]] | ||
| + | [[Category: Crawley L]] | ||
| + | [[Category: Edwards A]] | ||
| + | [[Category: Gileadi C]] | ||
| + | [[Category: Goubin S]] | ||
| + | [[Category: Johansson C]] | ||
| + | [[Category: Krojer T]] | ||
| + | [[Category: Oppermann U]] | ||
| + | [[Category: Szykowska A]] | ||
| + | [[Category: Vollmar M]] | ||
| + | [[Category: Von Delft F]] | ||
Current revision
Crystal structure of JmjC domain of human histone 3 Lysine-specific demethylase 3B (KDM3B)
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bountra C | Crawley L | Edwards A | Gileadi C | Goubin S | Johansson C | Krojer T | Oppermann U | Szykowska A | Vollmar M | Von Delft F
