4mro
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Human GKRP bound to AMG-5980 and S6P== | |
| + | <StructureSection load='4mro' size='340' side='right'caption='[[4mro]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4mro]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MRO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MRO FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=MG0:2-(4-{4-[(6-AMINOPYRIDIN-3-YL)SULFONYL]PIPERAZIN-1-YL}PHENYL)-1,1,1,3,3,3-HEXAFLUOROPROPAN-2-OL'>MG0</scene>, <scene name='pdbligand=S6P:D-SORBITOL-6-PHOSPHATE'>S6P</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mro FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mro OCA], [https://pdbe.org/4mro PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mro RCSB], [https://www.ebi.ac.uk/pdbsum/4mro PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mro ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/GCKR_HUMAN GCKR_HUMAN] Inhibits glucokinase by forming an inactive complex with this enzyme. | ||
| - | + | ==See Also== | |
| - | + | *[[Glucokinase Regulatory Protein|Glucokinase Regulatory Protein]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Ashton KS]] | ||
| + | [[Category: Bartberger MD]] | ||
| + | [[Category: Chen J]] | ||
| + | [[Category: Chmait S]] | ||
| + | [[Category: Cupples R]] | ||
| + | [[Category: Fotsch C]] | ||
| + | [[Category: Galbreath E]] | ||
| + | [[Category: Hale C]] | ||
| + | [[Category: Helmering J]] | ||
| + | [[Category: Jordan SR]] | ||
| + | [[Category: Kunz K]] | ||
| + | [[Category: LLoyd DJ]] | ||
| + | [[Category: Liu L]] | ||
| + | [[Category: Michelsen K]] | ||
| + | [[Category: Nishimura N]] | ||
| + | [[Category: Norman MH]] | ||
| + | [[Category: Pennington LD]] | ||
| + | [[Category: Poon SF]] | ||
| + | [[Category: Sivits G]] | ||
| + | [[Category: St Jean DJ]] | ||
| + | [[Category: Stec MM]] | ||
| + | [[Category: Tamayo N]] | ||
| + | [[Category: Van G]] | ||
| + | [[Category: Yang K]] | ||
Current revision
Human GKRP bound to AMG-5980 and S6P
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Categories: Homo sapiens | Large Structures | Ashton KS | Bartberger MD | Chen J | Chmait S | Cupples R | Fotsch C | Galbreath E | Hale C | Helmering J | Jordan SR | Kunz K | LLoyd DJ | Liu L | Michelsen K | Nishimura N | Norman MH | Pennington LD | Poon SF | Sivits G | St Jean DJ | Stec MM | Tamayo N | Van G | Yang K
