4msu
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Human GKRP bound to AMG-6861 and Sorbitol-6-phosphate== | |
| + | <StructureSection load='4msu' size='340' side='right'caption='[[4msu]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4msu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MSU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MSU FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2EU:1,1,1,3,3,3-HEXAFLUORO-2-{4-[4-(THIOPHEN-2-YLSULFONYL)PIPERAZIN-1-YL]PHENYL}PROPAN-2-OL'>2EU</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=S6P:D-SORBITOL-6-PHOSPHATE'>S6P</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4msu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4msu OCA], [https://pdbe.org/4msu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4msu RCSB], [https://www.ebi.ac.uk/pdbsum/4msu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4msu ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/GCKR_HUMAN GCKR_HUMAN] Inhibits glucokinase by forming an inactive complex with this enzyme. | ||
| - | + | ==See Also== | |
| - | + | *[[Glucokinase Regulatory Protein|Glucokinase Regulatory Protein]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Andrews KL]] | ||
| + | [[Category: Ashton KS]] | ||
| + | [[Category: Bryan MC]] | ||
| + | [[Category: Chen J]] | ||
| + | [[Category: Chen K]] | ||
| + | [[Category: Chen M]] | ||
| + | [[Category: Chmait S]] | ||
| + | [[Category: Croghan M]] | ||
| + | [[Category: Cupples R]] | ||
| + | [[Category: Fotsch C]] | ||
| + | [[Category: Hale C]] | ||
| + | [[Category: Helmering J]] | ||
| + | [[Category: Jordan SR]] | ||
| + | [[Category: Kurzeja RJ]] | ||
| + | [[Category: Lloyd DJ]] | ||
| + | [[Category: Michelsen K]] | ||
| + | [[Category: Pennington LD]] | ||
| + | [[Category: Poon SF]] | ||
| + | [[Category: Sivits G]] | ||
| + | [[Category: St Jean DJ]] | ||
| + | [[Category: Van G]] | ||
| + | [[Category: Vonderfecht SL]] | ||
| + | [[Category: Wahl RC]] | ||
| + | [[Category: Zhang J]] | ||
Current revision
Human GKRP bound to AMG-6861 and Sorbitol-6-phosphate
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Categories: Homo sapiens | Large Structures | Andrews KL | Ashton KS | Bryan MC | Chen J | Chen K | Chen M | Chmait S | Croghan M | Cupples R | Fotsch C | Hale C | Helmering J | Jordan SR | Kurzeja RJ | Lloyd DJ | Michelsen K | Pennington LD | Poon SF | Sivits G | St Jean DJ | Van G | Vonderfecht SL | Wahl RC | Zhang J
