4c0j

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{{STRUCTURE_4c0j| PDB=4c0j | SCENE= }}
 
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===Crystal structure of Drosophila Miro EF hand and cGTPase domains in the apo state (Apo-MiroS)===
 
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{{ABSTRACT_PUBMED_24071720}}
 
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==Function==
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==Crystal structure of Drosophila Miro EF hand and cGTPase domains in the apo state (Apo-MiroS)==
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[[http://www.uniprot.org/uniprot/MIRO_DROME MIRO_DROME]] Mitochondrial GTPase involved in mitochondrial trafficking. Milt and Miro form an essential protein complex that links Khc to mitochondria for light chain-independent, anterograde transport of mitochondria. Required for axonal transport to synapses within nerve terminals. Required presynaptically but not postsynaptically at neuromuscular junctions (NMJs).<ref>PMID:16055062</ref> <ref>PMID:16717129</ref>
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<StructureSection load='4c0j' size='340' side='right'caption='[[4c0j]], [[Resolution|resolution]] 2.82&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4c0j]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C0J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4C0J FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.82&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HSE:L-HOMOSERINE'>HSE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4c0j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c0j OCA], [https://pdbe.org/4c0j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4c0j RCSB], [https://www.ebi.ac.uk/pdbsum/4c0j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4c0j ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/MIRO_DROME MIRO_DROME] Mitochondrial GTPase involved in mitochondrial trafficking. Milt and Miro form an essential protein complex that links Khc to mitochondria for light chain-independent, anterograde transport of mitochondria. Required for axonal transport to synapses within nerve terminals. Required presynaptically but not postsynaptically at neuromuscular junctions (NMJs).<ref>PMID:16055062</ref> <ref>PMID:16717129</ref>
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==About this Structure==
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==See Also==
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[[4c0j]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C0J OCA].
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*[[Rho GTPase 3D structures|Rho GTPase 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:024071720</ref><references group="xtra"/><references/>
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__TOC__
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</StructureSection>
[[Category: Drosophila melanogaster]]
[[Category: Drosophila melanogaster]]
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[[Category: Chakravarthy, S.]]
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[[Category: Large Structures]]
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[[Category: Focia, P J.]]
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[[Category: Chakravarthy S]]
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[[Category: Freymann, D M.]]
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[[Category: Focia PJ]]
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[[Category: Klosowiak, J L.]]
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[[Category: Freymann DM]]
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[[Category: Landahl, E C.]]
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[[Category: Klosowiak JL]]
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[[Category: Rice, S E.]]
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[[Category: Landahl EC]]
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[[Category: Wawrzak, Z.]]
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[[Category: Rice SE]]
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[[Category: Calcium-binding gtpase]]
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[[Category: Wawrzak Z]]
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[[Category: Hidden ef hand]]
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[[Category: Hydrolase]]
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[[Category: Kinesin]]
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[[Category: Mitochondrial transport]]
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[[Category: Mitophagy]]
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Current revision

Crystal structure of Drosophila Miro EF hand and cGTPase domains in the apo state (Apo-MiroS)

PDB ID 4c0j

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