2p1j

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:07, 21 February 2024) (edit) (undo)
 
(17 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2p1j.gif|left|200px]]<br /><applet load="2p1j" size="350" color="white" frame="true" align="right" spinBox="true"
 
-
caption="2p1j, resolution 2.500&Aring;" />
 
-
'''Crystal structure of a polC-type DNA polymerase III exonuclease domain from Thermotoga maritima'''<br />
 
-
==About this Structure==
+
==Crystal structure of a polC-type DNA polymerase III exonuclease domain from Thermotoga maritima==
-
2P1J is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Active as [http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P1J OCA].
+
<StructureSection load='2p1j' size='340' side='right'caption='[[2p1j]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
-
[[Category: DNA-directed DNA polymerase]]
+
== Structural highlights ==
-
[[Category: Single protein]]
+
<table><tr><td colspan='2'>[[2p1j]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima_MSB8 Thermotoga maritima MSB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P1J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2P1J FirstGlance]. <br>
-
[[Category: Thermotoga maritima]]
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
-
[[Category: Almo, S C.]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2p1j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p1j OCA], [https://pdbe.org/2p1j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2p1j RCSB], [https://www.ebi.ac.uk/pdbsum/2p1j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2p1j ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2p1j TOPSAN]</span></td></tr>
-
[[Category: Bain, K T.]]
+
</table>
-
[[Category: Bonanno, J B.]]
+
== Function ==
-
[[Category: Burley, S K.]]
+
[https://www.uniprot.org/uniprot/DPO3_THEMA DPO3_THEMA] Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
-
[[Category: Izuka, M.]]
+
== Evolutionary Conservation ==
-
[[Category: NYSGXRC, New York Structural GenomiX Research Consortium.]]
+
[[Image:Consurf_key_small.gif|200px|right]]
-
[[Category: Rutter, M.]]
+
Check<jmol>
-
[[Category: Sauder, M J.]]
+
<jmolCheckbox>
-
[[Category: Smith, D.]]
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p1/2p1j_consurf.spt"</scriptWhenChecked>
-
[[Category: Sridhar, V.]]
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
[[Category: Wasserman, S.]]
+
<text>to colour the structure by Evolutionary Conservation</text>
-
[[Category: exonuclease]]
+
</jmolCheckbox>
-
[[Category: new york structural genomix research consortium]]
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2p1j ConSurf].
-
[[Category: nysgxrc]]
+
<div style="clear:both"></div>
-
[[Category: protein structure initiative]]
+
-
[[Category: psi-2]]
+
-
[[Category: structural genomics]]
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:24:48 2008''
+
==See Also==
 +
*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
 +
[[Category: Thermotoga maritima MSB8]]
 +
[[Category: Almo SC]]
 +
[[Category: Bain KT]]
 +
[[Category: Bonanno JB]]
 +
[[Category: Burley SK]]
 +
[[Category: Izuka M]]
 +
[[Category: Rutter M]]
 +
[[Category: Sauder JM]]
 +
[[Category: Smith D]]
 +
[[Category: Sridhar V]]
 +
[[Category: Wasserman S]]

Current revision

Crystal structure of a polC-type DNA polymerase III exonuclease domain from Thermotoga maritima

PDB ID 2p1j

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2p1j"
Personal tools