4k7k
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| - | {{STRUCTURE_4k7k| PDB=4k7k | SCENE= }} | ||
| - | ===Crystal structures of CusC review conformational changes accompanying folding and transmembrane channel formation=== | ||
| - | {{ABSTRACT_PUBMED_24099674}} | ||
| - | == | + | ==Crystal structures of CusC review conformational changes accompanying folding and transmembrane channel formation== |
| - | [[4k7k]] is a 2 chain structure with sequence from [ | + | <StructureSection load='4k7k' size='340' side='right'caption='[[4k7k]], [[Resolution|resolution]] 2.53Å' scene=''> |
| - | + | == Structural highlights == | |
| - | == | + | <table><tr><td colspan='2'>[[4k7k]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K7K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K7K FirstGlance]. <br> |
| - | < | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.53Å</td></tr> |
| - | [[Category: Escherichia coli | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k7k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k7k OCA], [https://pdbe.org/4k7k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k7k RCSB], [https://www.ebi.ac.uk/pdbsum/4k7k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k7k ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/CUSC_ECOLI CUSC_ECOLI] Part of a cation efflux system that mediates resistance to copper and silver. In pathogenic strains it allows the bacteria to invade brain microvascular endothelial cells (BMEC) thus allowing it to cross the blood-brain barrier and cause neonatal meningitis.<ref>PMID:11399769</ref> <ref>PMID:12813074</ref> |
| - | + | == References == | |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Escherichia coli K-12]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Lei H-T]] | ||
| + | [[Category: Su C-C]] | ||
Current revision
Crystal structures of CusC review conformational changes accompanying folding and transmembrane channel formation
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