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4f14

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{{STRUCTURE_4f14| PDB=4f14 | SCENE= }}
 
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===Structure of the SH3 domain of human nebulette in complex with a peptide of XIRP2===
 
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{{ABSTRACT_PUBMED_23985323}}
 
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==Function==
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==Structure of the SH3 domain of human nebulette in complex with a peptide of XIRP2==
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[[http://www.uniprot.org/uniprot/NEBL_HUMAN NEBL_HUMAN]] Binds to actin and plays an important role in the assembly of the Z-disk. Isoform 2 might play a role in the assembly of focal adhesion.<ref>PMID:15004028</ref> [[http://www.uniprot.org/uniprot/XIRP2_HUMAN XIRP2_HUMAN]] Protects actin filaments from depolymerization.
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<StructureSection load='4f14' size='340' side='right'caption='[[4f14]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[4f14]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F14 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4F14 FirstGlance]. <br>
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[[4f14]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F14 OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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==Reference==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4f14 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f14 OCA], [https://pdbe.org/4f14 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4f14 RCSB], [https://www.ebi.ac.uk/pdbsum/4f14 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4f14 ProSAT]</span></td></tr>
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<ref group="xtra">PMID:023985323</ref><references group="xtra"/><references/>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/NEBL_HUMAN NEBL_HUMAN] Binds to actin and plays an important role in the assembly of the Z-disk. Isoform 2 might play a role in the assembly of focal adhesion.<ref>PMID:15004028</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Sauer, F.]]
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[[Category: Large Structures]]
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[[Category: Vahokoski, J.]]
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[[Category: Sauer F]]
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[[Category: Wilmanns, M.]]
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[[Category: Vahokoski J]]
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[[Category: Actin-binding protein-peptide complex]]
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[[Category: Wilmanns M]]
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[[Category: Heart muscle]]
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[[Category: Sh3 domain]]
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Current revision

Structure of the SH3 domain of human nebulette in complex with a peptide of XIRP2

PDB ID 4f14

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