2mfo
From Proteopedia
(Difference between revisions)
m (Protected "2mfo" [edit=sysop:move=sysop]) |
|||
| (6 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Solution structure of the C-terminally encoded peptide of the model plant host Medicago truncatula - CEP1== | |
| + | <StructureSection load='2mfo' size='340' side='right'caption='[[2mfo]]' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2mfo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Medicago_truncatula Medicago truncatula]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MFO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MFO FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HZP:(4S)-4-HYDROXY-L-PROLINE'>HZP</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mfo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mfo OCA], [https://pdbe.org/2mfo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mfo RCSB], [https://www.ebi.ac.uk/pdbsum/2mfo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mfo ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/G7K427_MEDTR G7K427_MEDTR] | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The C-terminally Encoded Peptide (CEP) family of regulatory peptides controls root development in vascular plants. Here, we present the first NMR structures of CEP. We show that root-knot nematode (RKN: Meloidogyne spp.) also encodes CEP, presumably to mimic plant CEP as part of their stereotypic, parasitic interaction with vascular plants. Molecular dynamics simulations of plant- and nematode-encoded CEP displaying known posttranslational modifications (PTM) provided insight into the structural effects of PTM and the conformational plasticity and rigidity of CEP. Potential mechanisms of action are discussed with respect to the structure and sampling of conformational space. | ||
| - | + | Solution NMR studies of the plant peptide hormone CEP inform function.,Bobay BG, Digennaro P, Scholl E, Imin N, Djordjevic MA, McK Bird D FEBS Lett. 2013 Dec 11;587(24):3979-85. doi: 10.1016/j.febslet.2013.10.033. Epub , 2013 Nov 5. PMID:24211833<ref>PMID:24211833</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| + | </div> | ||
| + | <div class="pdbe-citations 2mfo" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Medicago truncatula]] | ||
| + | [[Category: Bird DM]] | ||
| + | [[Category: Bobay BG]] | ||
| + | [[Category: DiGennaro P]] | ||
Current revision
Solution structure of the C-terminally encoded peptide of the model plant host Medicago truncatula - CEP1
| |||||||||||
