4khw

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{{STRUCTURE_4khw| PDB=4khw | SCENE= }}
 
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===Ternary complex of RB69 mutant L415F with ribonucleotide at -2 position===
 
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{{ABSTRACT_PUBMED_24082122}}
 
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==Function==
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==Ternary complex of RB69 mutant L415F with ribonucleotide at -2 position==
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[[http://www.uniprot.org/uniprot/DPOL_BPR69 DPOL_BPR69]] This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3'- to 5'-direction.
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<StructureSection load='4khw' size='340' side='right'caption='[[4khw]], [[Resolution|resolution]] 2.37&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4khw]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_phage_RB69 Escherichia phage RB69]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KHW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KHW FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.371&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=TTP:THYMIDINE-5-TRIPHOSPHATE'>TTP</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4khw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4khw OCA], [https://pdbe.org/4khw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4khw RCSB], [https://www.ebi.ac.uk/pdbsum/4khw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4khw ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DPOL_BPR69 DPOL_BPR69] This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3'- to 5'-direction.
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==About this Structure==
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==See Also==
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[[4khw]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_rb69 Enterobacteria phage rb69]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KHW OCA].
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*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:024082122</ref><references group="xtra"/><references/>
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[[Category: Escherichia phage RB69]]
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[[Category: DNA-directed DNA polymerase]]
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[[Category: Large Structures]]
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[[Category: Enterobacteria phage rb69]]
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[[Category: Clausen AR]]
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[[Category: Clausen, A R.]]
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[[Category: Pedersen LC]]
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[[Category: Pedersen, L C.]]
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[[Category: Ribonucleotide]]
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[[Category: Transferase-dna complex]]
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Current revision

Ternary complex of RB69 mutant L415F with ribonucleotide at -2 position

PDB ID 4khw

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