This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3ar6

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:40, 7 February 2024) (edit) (undo)
 
(5 intermediate revisions not shown.)
Line 1: Line 1:
-
{{STRUCTURE_3ar6| PDB=3ar6 | SCENE= }}
 
-
===Calcium pump crystal structure with bound TNP-ADP and TG in the absence of calcium===
 
-
{{ABSTRACT_PUBMED_21239683}}
 
-
==Function==
+
==Calcium pump crystal structure with bound TNP-ADP and TG in the absence of calcium==
-
[[http://www.uniprot.org/uniprot/AT2A1_RABIT AT2A1_RABIT]] This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction (By similarity).
+
<StructureSection load='3ar6' size='340' side='right'caption='[[3ar6]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
-
 
+
== Structural highlights ==
-
==About this Structure==
+
<table><tr><td colspan='2'>[[3ar6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AR6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AR6 FirstGlance]. <br>
-
[[3ar6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AR6 OCA].
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=12D:2,3-O-[(1R,6R)-2,4,6-TRINITROCYCLOHEXA-2,4-DIENE-1,1-DIYL]ADENOSINE+5-(TRIHYDROGEN+DIPHOSPHATE)'>12D</scene>, <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PTY:PHOSPHATIDYLETHANOLAMINE'>PTY</scene>, <scene name='pdbligand=TG1:OCTANOIC+ACID+[3S-[3ALPHA,+3ABETA,+4ALPHA,+6BETA,+6ABETA,+7BETA,+8ALPHA(Z),+9BALPHA]]-6-(ACETYLOXY)-2,3,-3A,4,5,6,6A,7,8,9B-DECAHYDRO-3,3A-DIHYDROXY-3,6,9-TRIMETHYL-8-[(2-METHYL-1-OXO-2-BUTENYL)OX+Y]-2-OXO-4-(1-OXOBUTOXY)-AZULENO[4,5-B]FURAN-7-YL+ESTER'>TG1</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ar6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ar6 OCA], [https://pdbe.org/3ar6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ar6 RCSB], [https://www.ebi.ac.uk/pdbsum/3ar6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ar6 ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/AT2A1_RABIT AT2A1_RABIT] This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction (By similarity).
==See Also==
==See Also==
-
*[[ATPase|ATPase]]
+
*[[ATPase 3D structures|ATPase 3D structures]]
-
 
+
__TOC__
-
==Reference==
+
</StructureSection>
-
<ref group="xtra">PMID:021239683</ref><references group="xtra"/><references/>
+
[[Category: Large Structures]]
-
[[Category: Calcium-transporting ATPase]]
+
[[Category: Oryctolagus cuniculus]]
[[Category: Oryctolagus cuniculus]]
-
[[Category: Iwasawa, S.]]
+
[[Category: Iwasawa S]]
-
[[Category: Toyoshima, C.]]
+
[[Category: Toyoshima C]]
-
[[Category: Tsueda, J.]]
+
[[Category: Tsueda J]]
-
[[Category: Yonekura, S.]]
+
[[Category: Yonekura S]]
-
[[Category: Atp binding]]
+
-
[[Category: Calcium binding]]
+
-
[[Category: Calcium transport]]
+
-
[[Category: Endoplasmic reticulum]]
+
-
[[Category: Hydrolase]]
+
-
[[Category: Hydrolase-hydrolase inhibitor complex]]
+
-
[[Category: P-type atpase]]
+
-
[[Category: Sarcoplasmic reticulum]]
+

Current revision

Calcium pump crystal structure with bound TNP-ADP and TG in the absence of calcium

PDB ID 3ar6

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools