4isa

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{{STRUCTURE_4isa| PDB=4isa | SCENE= }}
 
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===Crystal Structure of the Escherichia coli LpxC/BB-78485 complex===
 
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{{ABSTRACT_PUBMED_24117400}}
 
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==Function==
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==Crystal Structure of the Escherichia coli LpxC/BB-78485 complex==
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[[http://www.uniprot.org/uniprot/D5CV28_ECOKI D5CV28_ECOKI]] Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity).[HAMAP-Rule:MF_00388][SAAS:SAAS004463_004_013136]
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<StructureSection load='4isa' size='340' side='right'caption='[[4isa]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4isa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_IHE3034 Escherichia coli IHE3034]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ISA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ISA FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=D1D:(4S,5S)-1,2-DITHIANE-4,5-DIOL'>D1D</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GVR:(2R)-N-HYDROXY-3-NAPHTHALEN-2-YL-2-[(NAPHTHALEN-2-YLSULFONYL)AMINO]PROPANAMIDE'>GVR</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4isa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4isa OCA], [https://pdbe.org/4isa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4isa RCSB], [https://www.ebi.ac.uk/pdbsum/4isa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4isa ProSAT]</span></td></tr>
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</table>
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==About this Structure==
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==See Also==
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[[4isa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_ihe3034 Escherichia coli ihe3034]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ISA OCA].
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*[[UDP-3-O-acyl-N-acetylglucosamine deacetylase|UDP-3-O-acyl-N-acetylglucosamine deacetylase]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:024117400</ref><references group="xtra"/><references/>
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[[Category: Escherichia coli IHE3034]]
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[[Category: Escherichia coli ihe3034]]
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[[Category: Large Structures]]
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[[Category: Lee, C J.]]
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[[Category: Lee C-J]]
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[[Category: Zhou, P.]]
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[[Category: Zhou P]]
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[[Category: Acyl udp-glcnac]]
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[[Category: Antibiotic]]
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[[Category: Baab sandwich]]
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[[Category: Bb-78485]]
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[[Category: Deacetylation]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Hydroxamate]]
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[[Category: Lipid a synthesis]]
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[[Category: Lpxc]]
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Current revision

Crystal Structure of the Escherichia coli LpxC/BB-78485 complex

PDB ID 4isa

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