2pkt

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[[Image:2pkt.jpg|left|200px]]<br /><applet load="2pkt" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="2pkt, resolution 1.500&Aring;" />
 
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'''Crystal structure of the human CLP-36 (PDLIM1) bound to the C-terminal peptide of human alpha-actinin-1'''<br />
 
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==About this Structure==
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==Crystal structure of the human CLP-36 (PDLIM1) bound to the C-terminal peptide of human alpha-actinin-1==
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2PKT is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=CA:'>CA</scene>, <scene name='pdbligand=CL:'>CL</scene>, <scene name='pdbligand=ACT:'>ACT</scene>, <scene name='pdbligand=PG4:'>PG4</scene> and <scene name='pdbligand=PEG:'>PEG</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PKT OCA].
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<StructureSection load='2pkt' size='340' side='right'caption='[[2pkt]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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[[Category: Homo sapiens]]
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== Structural highlights ==
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[[Category: Single protein]]
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<table><tr><td colspan='2'>[[2pkt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PKT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PKT FirstGlance]. <br>
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[[Category: Arrowsmith, C H.]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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[[Category: Bray, J.]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
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[[Category: Bunkoczi, G.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pkt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pkt OCA], [https://pdbe.org/2pkt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pkt RCSB], [https://www.ebi.ac.uk/pdbsum/2pkt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pkt ProSAT]</span></td></tr>
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[[Category: Burgess-Brown, N.]]
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</table>
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[[Category: Delft, F von.]]
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== Function ==
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[[Category: Doyle, D A.]]
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[https://www.uniprot.org/uniprot/PDLI1_HUMAN PDLI1_HUMAN] Cytoskeletal protein that may act as an adapter that brings other proteins (like kinases) to the cytoskeleton.
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[[Category: Edwards, A.]]
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== Evolutionary Conservation ==
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[[Category: Elkins, J.]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Gileadi, C.]]
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Check<jmol>
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[[Category: Gileadi, O.]]
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<jmolCheckbox>
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[[Category: SGC, Structural Genomics Consortium.]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pk/2pkt_consurf.spt"</scriptWhenChecked>
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[[Category: Salah, E.]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: Sundstrom, M.]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Ugochukwu, E.]]
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</jmolCheckbox>
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[[Category: Umeano, C.]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pkt ConSurf].
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[[Category: Uppenberg, J.]]
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<div style="clear:both"></div>
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[[Category: Weigelt, J.]]
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[[Category: ACT]]
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[[Category: CA]]
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[[Category: CL]]
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[[Category: PEG]]
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[[Category: PG4]]
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[[Category: pdz domain]]
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[[Category: sgc]]
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[[Category: structural genomics]]
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[[Category: structural genomics consortium]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:30:32 2008''
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==See Also==
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*[[PDZ and LIM domain protein|PDZ and LIM domain protein]]
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Arrowsmith CH]]
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[[Category: Bray J]]
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[[Category: Bunkoczi G]]
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[[Category: Burgess-Brown N]]
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[[Category: Doyle DA]]
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[[Category: Edwards A]]
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[[Category: Elkins J]]
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[[Category: Gileadi C]]
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[[Category: Gileadi O]]
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[[Category: Salah E]]
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[[Category: Sundstrom M]]
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[[Category: Ugochukwu E]]
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[[Category: Umeano C]]
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[[Category: Uppenberg J]]
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[[Category: Weigelt J]]
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[[Category: Von Delft F]]

Current revision

Crystal structure of the human CLP-36 (PDLIM1) bound to the C-terminal peptide of human alpha-actinin-1

PDB ID 2pkt

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