2por

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[[Image:2por.gif|left|200px]]<br /><applet load="2por" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="2por, resolution 1.8&Aring;" />
 
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'''STRUCTURE OF PORIN REFINED AT 1.8 ANGSTROMS RESOLUTION'''<br />
 
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==Overview==
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==STRUCTURE OF PORIN REFINED AT 1.8 ANGSTROMS RESOLUTION==
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The crystal structure of porin from Rhodobacter capsulatus has been refined using the simulated annealing method. The final model consists of all 301 amino acid residues well obeying standard geometry, three calcium ions, 274 solvent molecules, three detergent molecules and one unknown ligand modeled as a detergent molecule. The final crystallographic R-factor is 18.6% based on 42,851 independent reflections in the resolution range 10 to 1.8 A. The model is described in detail.
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<StructureSection load='2por' size='340' side='right'caption='[[2por]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2por]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodobacter_capsulatus Rhodobacter capsulatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2POR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2POR FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C8E:(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE'>C8E</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2por FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2por OCA], [https://pdbe.org/2por PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2por RCSB], [https://www.ebi.ac.uk/pdbsum/2por PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2por ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PORI_RHOCA PORI_RHOCA] Forms channels that allow the passive diffusion of small hydrophilic solutes up to an exclusion limit of about 0.6 kDa.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/po/2por_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2por ConSurf].
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<div style="clear:both"></div>
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==About this Structure==
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==See Also==
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2POR is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Rhodobacter_capsulatus Rhodobacter capsulatus] with <scene name='pdbligand=CA:'>CA</scene> and <scene name='pdbligand=C8E:'>C8E</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2POR OCA].
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*[[Porin 3D structures|Porin 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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Structure of porin refined at 1.8 A resolution., Weiss MS, Schulz GE, J Mol Biol. 1992 Sep 20;227(2):493-509. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=1328651 1328651]
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[[Category: Large Structures]]
[[Category: Rhodobacter capsulatus]]
[[Category: Rhodobacter capsulatus]]
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[[Category: Single protein]]
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[[Category: Schulz GE]]
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[[Category: Schulz, G E.]]
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[[Category: Weiss MS]]
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[[Category: Weiss, M S.]]
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[[Category: C8E]]
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[[Category: CA]]
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[[Category: integral membrane protein porin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:31:39 2008''
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Current revision

STRUCTURE OF PORIN REFINED AT 1.8 ANGSTROMS RESOLUTION

PDB ID 2por

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