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2pr2
From Proteopedia
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| - | [[Image:2pr2.jpg|left|200px]]<br /><applet load="2pr2" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2pr2, resolution 2.500Å" /> | ||
| - | '''Structure of Mycobacterium tuberculosis enoyl-ACP reductase with bound INH-NADP.'''<br /> | ||
| - | == | + | ==Structure of Mycobacterium tuberculosis enoyl-ACP reductase with bound INH-NADP.== |
| - | + | <StructureSection load='2pr2' size='340' side='right'caption='[[2pr2]], [[Resolution|resolution]] 2.50Å' scene=''> | |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2pr2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PR2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PR2 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DG1:(4S)-ISONICOTINIC-ACETYL-NICOTINAMIDE-ADENINE+DINUCLEOTIDE'>DG1</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pr2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pr2 OCA], [https://pdbe.org/2pr2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pr2 RCSB], [https://www.ebi.ac.uk/pdbsum/2pr2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pr2 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/INHA_MYCTU INHA_MYCTU] | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pr/2pr2_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pr2 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | + | *[[Enoyl-Acyl-Carrier Protein Reductase 3D structures|Enoyl-Acyl-Carrier Protein Reductase 3D structures]] | |
| - | [ | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Argyrou | + | [[Category: Mycobacterium tuberculosis H37Rv]] |
| - | [[Category: Blanchard | + | [[Category: Argyrou A]] |
| - | [[Category: Vetting | + | [[Category: Blanchard JS]] |
| - | + | [[Category: Vetting MW]] | |
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Current revision
Structure of Mycobacterium tuberculosis enoyl-ACP reductase with bound INH-NADP.
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