4icx

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'''Unreleased structure'''
 
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The entry 4icx is ON HOLD until Jun 11 2015
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==N-terminal C2 domain of human CEP120==
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<StructureSection load='4icx' size='340' side='right'caption='[[4icx]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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Authors: Janowski, R., Guarin, N., Coll, M.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4icx]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ICX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ICX FirstGlance]. <br>
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Description: N-terminal C2 domain of human CEP120
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4icx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4icx OCA], [https://pdbe.org/4icx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4icx RCSB], [https://www.ebi.ac.uk/pdbsum/4icx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4icx ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CE120_HUMAN CE120_HUMAN] Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors and for proper positioning of neurons during brain development. Also implicated in the migration and selfrenewal of neural progenitors. May play a role in centriole duplication during mitosis (By similarity).
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Coll M]]
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[[Category: Guarin N]]
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[[Category: Janowski R]]

Current revision

N-terminal C2 domain of human CEP120

PDB ID 4icx

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