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4nb5
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of a transcriptional regulator== | |
| - | + | <StructureSection load='4nb5' size='340' side='right'caption='[[4nb5]], [[Resolution|resolution]] 1.64Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4nb5]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NB5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NB5 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.641Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2JT:1,3-DIHYDROXYPROPAN-2-YL+OCTADECANOATE'>2JT</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nb5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nb5 OCA], [https://pdbe.org/4nb5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nb5 RCSB], [https://www.ebi.ac.uk/pdbsum/4nb5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nb5 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MMPR5_MYCTU MMPR5_MYCTU] Controls the expression level of the Mmps2-MmpL2, MmpS4-MmpL4, and MmpS5-MmpL5 transport systems. Also controls its own expression. Acts by binding directly to the promoter regions.<ref>PMID:18851927</ref> <ref>PMID:24590481</ref> <ref>PMID:24737322</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mycobacterium tuberculosis H37Rv]] | ||
| + | [[Category: Radhakrishnan A]] | ||
| + | [[Category: Su C-C]] | ||
| + | [[Category: Yu EW]] | ||
Current revision
Crystal Structure of a transcriptional regulator
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