2pwp

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[[Image:2pwp.gif|left|200px]]<br /><applet load="2pwp" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="2pwp, resolution 2.1&Aring;" />
 
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'''Crystal structure of spermidine synthase from Plasmodium falciparum in complex with spermidine'''<br />
 
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==About this Structure==
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==Crystal structure of spermidine synthase from Plasmodium falciparum in complex with spermidine==
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2PWP is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum_3d7 Plasmodium falciparum 3d7] with <scene name='pdbligand=SPD:'>SPD</scene>, <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Spermidine_synthase Spermidine synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.16 2.5.1.16] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PWP OCA].
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<StructureSection load='2pwp' size='340' side='right'caption='[[2pwp]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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[[Category: Plasmodium falciparum 3d7]]
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== Structural highlights ==
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[[Category: Single protein]]
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<table><tr><td colspan='2'>[[2pwp]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_3D7 Plasmodium falciparum 3D7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PWP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PWP FirstGlance]. <br>
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[[Category: Spermidine synthase]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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[[Category: Arrowsmith, C H.]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=SPD:SPERMIDINE'>SPD</scene></td></tr>
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[[Category: Bochkarev, A.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pwp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pwp OCA], [https://pdbe.org/2pwp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pwp RCSB], [https://www.ebi.ac.uk/pdbsum/2pwp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pwp ProSAT]</span></td></tr>
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[[Category: Dong, A.]]
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</table>
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[[Category: Edwards, A M.]]
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== Function ==
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[[Category: Hui, R.]]
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[https://www.uniprot.org/uniprot/Q8II73_PLAF7 Q8II73_PLAF7]
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[[Category: Kozieradzki, I.]]
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== Evolutionary Conservation ==
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[[Category: Lew, J.]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Plotnikov, A N.]]
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Check<jmol>
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[[Category: Qiu, W.]]
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<jmolCheckbox>
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[[Category: Ren, H.]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pw/2pwp_consurf.spt"</scriptWhenChecked>
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[[Category: SGC, Structural Genomics Consortium.]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: Schapira, M.]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Sundstrom, M.]]
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</jmolCheckbox>
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[[Category: Vedadi, M.]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pwp ConSurf].
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[[Category: Wasney, G.]]
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<div style="clear:both"></div>
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[[Category: Weigelt, J.]]
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[[Category: Wu, H.]]
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[[Category: Zhao, Y.]]
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[[Category: GOL]]
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[[Category: SO4]]
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[[Category: SPD]]
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[[Category: sgc]]
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[[Category: spermidine]]
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[[Category: spermidine synthase]]
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[[Category: structural genomics consortium]]
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[[Category: transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:33:43 2008''
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==See Also==
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*[[Spermidine synthase 3D structures|Spermidine synthase 3D structures]]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Plasmodium falciparum 3D7]]
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[[Category: Arrowsmith CH]]
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[[Category: Bochkarev A]]
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[[Category: Dong A]]
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[[Category: Edwards AM]]
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[[Category: Hui R]]
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[[Category: Kozieradzki I]]
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[[Category: Lew J]]
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[[Category: Plotnikov AN]]
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[[Category: Qiu W]]
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[[Category: Ren H]]
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[[Category: Schapira M]]
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[[Category: Sundstrom M]]
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[[Category: Vedadi M]]
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[[Category: Wasney G]]
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[[Category: Weigelt J]]
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[[Category: Wu H]]
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[[Category: Zhao Y]]

Current revision

Crystal structure of spermidine synthase from Plasmodium falciparum in complex with spermidine

PDB ID 2pwp

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