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4n6w
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==X-Ray Crystal Structure of Citrate-bound PhnZ== | |
| - | + | <StructureSection load='4n6w' size='340' side='right'caption='[[4n6w]], [[Resolution|resolution]] 1.85Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4n6w]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Uncultured_bacterium_HF130_AEPn_1 Uncultured bacterium HF130_AEPn_1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N6W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4N6W FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4n6w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n6w OCA], [https://pdbe.org/4n6w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4n6w RCSB], [https://www.ebi.ac.uk/pdbsum/4n6w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4n6w ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PHNZ_UNCHF PHNZ_UNCHF] Involved in the degradation of the organophosphonate 2-aminoethylphosphonic acid (2-AEP) (Probable). Catalyzes the cleavage of the carbon-phosphorus bond of (2-amino-1-hydroxyethyl)phosphonic acid to yield glycine and phosphate through an oxidative mechanism (PubMed:22564006, PubMed:24198335, PubMed:24706911). It reacts stereospecifically with the R-enantiomer of (2-amino-1-hydroxyethyl)phosphonic acid and is also able to use (R,R)-2-amino-1-hydroxypropylphosphonate as substrate (PubMed:24706911).<ref>PMID:22564006</ref> <ref>PMID:24198335</ref> <ref>PMID:24706911</ref> <ref>PMID:19788654</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Uncultured bacterium HF130_AEPn_1]] | ||
| + | [[Category: Boal AK]] | ||
| + | [[Category: Bollinger Jr JM]] | ||
| + | [[Category: Krebs C]] | ||
| + | [[Category: Lingaraju M]] | ||
| + | [[Category: Pandelia ME]] | ||
| + | [[Category: Worsdorfer B]] | ||
| + | [[Category: Yennawar NH]] | ||
Current revision
X-Ray Crystal Structure of Citrate-bound PhnZ
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