4lp0

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{{STRUCTURE_4lp0| PDB=4lp0 | SCENE= }}
 
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===Crystal structure of a topoisomerase ATP inhibitor===
 
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{{ABSTRACT_PUBMED_24098982}}
 
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==About this Structure==
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==Crystal structure of a topoisomerase ATP inhibitor==
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[[4lp0]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LP0 OCA].
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<StructureSection load='4lp0' size='340' side='right'caption='[[4lp0]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4lp0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_R6 Streptococcus pneumoniae R6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LP0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LP0 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1YM:6-[(ETHYLCARBAMOYL)AMINO]-4-[4-(TRIFLUOROMETHYL)-1,3-THIAZOL-2-YL]-3,3-BIPYRIDINE-5-CARBOXYLIC+ACID'>1YM</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lp0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lp0 OCA], [https://pdbe.org/4lp0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lp0 RCSB], [https://www.ebi.ac.uk/pdbsum/4lp0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lp0 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q8DQB5_STRR6 Q8DQB5_STRR6]
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==Reference==
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==See Also==
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<ref group="xtra">PMID:024098982</ref><references group="xtra"/><references/>
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*[[Topoisomerase 3D structures|Topoisomerase 3D structures]]
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[[Category: Basarab, G S.]]
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__TOC__
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[[Category: Bist, S.]]
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</StructureSection>
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[[Category: Boriack-Sjodin, P A.]]
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[[Category: Large Structures]]
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[[Category: Dangel, B.]]
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[[Category: Streptococcus pneumoniae R6]]
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[[Category: Eakin, A E.]]
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[[Category: Basarab GS]]
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[[Category: Illingsworth, R.]]
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[[Category: Bist S]]
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[[Category: Manchester, J I.]]
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[[Category: Boriack-Sjodin PA]]
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[[Category: Sherer, B A.]]
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[[Category: Dangel B]]
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[[Category: Sriram, S.]]
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[[Category: Eakin AE]]
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[[Category: Uria-Nickelsen, M.]]
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[[Category: Illingsworth R]]
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[[Category: Antimicrobial]]
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[[Category: Manchester JI]]
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[[Category: Atp binding]]
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[[Category: Sherer BA]]
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[[Category: Atpase domain]]
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[[Category: Sriram S]]
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[[Category: Isomerase-isomerase inhibitor complex]]
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[[Category: Uria-Nickelsen M]]
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[[Category: Protein-inhibitor complex]]
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[[Category: Structure-based drug design]]
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[[Category: Virtual screen]]
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Current revision

Crystal structure of a topoisomerase ATP inhibitor

PDB ID 4lp0

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