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4ljz

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{{STRUCTURE_4ljz| PDB=4ljz | SCENE= }}
 
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===Crystal Structure Analysis of the E.coli holoenzyme===
 
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==Function==
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==Crystal Structure Analysis of the E.coli holoenzyme==
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[[http://www.uniprot.org/uniprot/C9QUL2_ECOD1 C9QUL2_ECOD1]] Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity).[HAMAP-Rule:MF_00366][SAAS:SAAS012293_004_017283] [[http://www.uniprot.org/uniprot/C9QXI7_ECOD1 C9QXI7_ECOD1]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity).[HAMAP-Rule:MF_00059] [[http://www.uniprot.org/uniprot/C5A0S8_ECOBW C5A0S8_ECOBW]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity).[SAAS:SAAS012754_004_011999] [[http://www.uniprot.org/uniprot/C9QV90_ECOD1 C9QV90_ECOD1]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity).[HAMAP-Rule:MF_01321][RuleBase:RU000432] [[http://www.uniprot.org/uniprot/RPOD_ECOLI RPOD_ECOLI]] Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This is the primary sigma factor of this bacterium.
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<StructureSection load='4ljz' size='340' side='right'caption='[[4ljz]], [[Resolution|resolution]] 3.59&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4ljz]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_BW2952 Escherichia coli BW2952], [https://en.wikipedia.org/wiki/Escherichia_coli_DH1 Escherichia coli DH1] and [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LJZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LJZ FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5871&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ljz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ljz OCA], [https://pdbe.org/4ljz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ljz RCSB], [https://www.ebi.ac.uk/pdbsum/4ljz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ljz ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RPOD_ECOLI RPOD_ECOLI] Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This is the primary sigma factor of this bacterium.
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==About this Structure==
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==See Also==
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[[4ljz]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LJZ OCA].
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*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
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[[Category: DNA-directed RNA polymerase]]
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*[[Sigma factor 3D structures|Sigma factor 3D structures]]
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[[Category: Bae, B.]]
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__TOC__
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[[Category: Darst, S A.]]
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</StructureSection>
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[[Category: Dna directed rna polymerase]]
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[[Category: Escherichia coli BW2952]]
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[[Category: Transferase]]
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[[Category: Escherichia coli DH1]]
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[[Category: Escherichia coli K-12]]
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[[Category: Large Structures]]
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[[Category: Bae B]]
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[[Category: Darst SA]]

Current revision

Crystal Structure Analysis of the E.coli holoenzyme

PDB ID 4ljz

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