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4nf2

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(New page: {{STRUCTURE_4nf2| PDB=4nf2 | SCENE= }} ===Crystal structure of anabolic ornithine carbamoyltransferase from Bacillus anthracis in complex with carbamoyl phosphate and L-norvaline=== ...)
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{{STRUCTURE_4nf2| PDB=4nf2 | SCENE= }}
 
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===Crystal structure of anabolic ornithine carbamoyltransferase from Bacillus anthracis in complex with carbamoyl phosphate and L-norvaline===
 
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==Function==
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==Crystal structure of anabolic ornithine carbamoyltransferase from Bacillus anthracis in complex with carbamoyl phosphate and L-norvaline==
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[[http://www.uniprot.org/uniprot/OTC_BACAN OTC_BACAN]] Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline, which is a substrate for argininosuccinate synthetase, the enzyme involved in the final step in arginine biosynthesis (By similarity).[HAMAP-Rule:MF_01109]
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<StructureSection load='4nf2' size='340' side='right'caption='[[4nf2]], [[Resolution|resolution]] 1.74&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4nf2]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis_str._'Ames_Ancestor' Bacillus anthracis str. 'Ames Ancestor']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NF2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NF2 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.74&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CP:PHOSPHORIC+ACID+MONO(FORMAMIDE)ESTER'>CP</scene>, <scene name='pdbligand=NVA:NORVALINE'>NVA</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nf2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nf2 OCA], [https://pdbe.org/4nf2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nf2 RCSB], [https://www.ebi.ac.uk/pdbsum/4nf2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nf2 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/OTC_BACAN OTC_BACAN] Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline, which is a substrate for argininosuccinate synthetase, the enzyme involved in the final step in arginine biosynthesis (By similarity).[HAMAP-Rule:MF_01109]
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==About this Structure==
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==See Also==
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[[4nf2]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NF2 OCA].
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*[[Ornithine carbamoyltransferase 3D structures|Ornithine carbamoyltransferase 3D structures]]
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[[Category: Ornithine carbamoyltransferase]]
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__TOC__
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[[Category: Anderson, W F.]]
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</StructureSection>
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[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
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[[Category: Bacillus anthracis str. 'Ames Ancestor']]
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[[Category: Cymborowski, M T.]]
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[[Category: Large Structures]]
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[[Category: Handing, K.]]
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[[Category: Anderson WF]]
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[[Category: Minor, W.]]
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[[Category: Cymborowski MT]]
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[[Category: Shabalin, I G.]]
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[[Category: Handing K]]
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[[Category: Shuvalova, L.]]
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[[Category: Minor W]]
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[[Category: Stam, J.]]
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[[Category: Shabalin IG]]
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[[Category: Winsor, J.]]
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[[Category: Shuvalova L]]
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[[Category: Carbamoyl phosphate]]
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[[Category: Stam J]]
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[[Category: Center for structural genomics of infectious disease]]
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[[Category: Winsor J]]
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[[Category: Csgid]]
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[[Category: L-ornithine]]
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[[Category: National institute of allergy and infectious disease]]
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[[Category: Niaid]]
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[[Category: Structural genomic]]
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[[Category: Transferase]]
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Current revision

Crystal structure of anabolic ornithine carbamoyltransferase from Bacillus anthracis in complex with carbamoyl phosphate and L-norvaline

PDB ID 4nf2

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