4nkb
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4nkb is ON HOLD Authors: Shimanovskaya, E. , Dong, G. Description: Crystal Structure of the cryptic polo box (CPB)of ZYG-1) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of the cryptic polo box (CPB)of ZYG-1== | |
| - | + | <StructureSection load='4nkb' size='340' side='right'caption='[[4nkb]], [[Resolution|resolution]] 2.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4nkb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NKB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NKB FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DTT:2,3-DIHYDROXY-1,4-DITHIOBUTANE'>DTT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nkb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nkb OCA], [https://pdbe.org/4nkb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nkb RCSB], [https://www.ebi.ac.uk/pdbsum/4nkb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nkb ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ZYG1_CAEEL ZYG1_CAEEL] Protein kinase that plays a central role in centrosome duplication. Paternal copy is required to regulate synthesis of daughter centrioles prior to fertilization. Maternal copy regulates centrosome duplication during later cell cycles. Functions upstream of sas-5 and sas-6, and is required for their localization to the centrosome.<ref>PMID:11371350</ref> <ref>PMID:15232593</ref> <ref>PMID:15665853</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Caenorhabditis elegans]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Dong G]] | ||
| + | [[Category: Shimanovskaya E]] | ||
Current revision
Crystal Structure of the cryptic polo box (CPB)of ZYG-1
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