This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3w1q
From Proteopedia
(Difference between revisions)
| (3 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | {{STRUCTURE_3w1q| PDB=3w1q | SCENE= }} | ||
| - | ===Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with NL-2=== | ||
| - | == | + | ==Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with NL-2== |
| - | [[http://www.uniprot.org/uniprot/PYRD_TRYCC PYRD_TRYCC | + | <StructureSection load='3w1q' size='340' side='right'caption='[[3w1q]], [[Resolution|resolution]] 1.85Å' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3w1q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_cruzi_strain_CL_Brener Trypanosoma cruzi strain CL Brener]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W1Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3W1Q FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene>, <scene name='pdbligand=YRO:5-(3,3-DIMETHYLBUTYL)-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC+ACID'>YRO</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3w1q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w1q OCA], [https://pdbe.org/3w1q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3w1q RCSB], [https://www.ebi.ac.uk/pdbsum/3w1q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3w1q ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PYRD_TRYCC PYRD_TRYCC] Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor. Molecular oxygen can replace fumarate in vitro. | ||
| - | == | + | ==See Also== |
| - | [[ | + | *[[Dihydroorotate dehydrogenase 3D structures|Dihydroorotate dehydrogenase 3D structures]] |
| - | [[Category: Aoki | + | __TOC__ |
| - | [[Category: Balogun | + | </StructureSection> |
| - | [[Category: Harada | + | [[Category: Large Structures]] |
| - | [[Category: Honma | + | [[Category: Trypanosoma cruzi strain CL Brener]] |
| - | [[Category: Iida | + | [[Category: Aoki T]] |
| - | [[Category: Inaoka | + | [[Category: Balogun EO]] |
| - | [[Category: Inoue | + | [[Category: Harada S]] |
| - | [[Category: Kita | + | [[Category: Honma T]] |
| - | [[Category: Lee | + | [[Category: Iida M]] |
| - | [[Category: Matsuoka | + | [[Category: Inaoka DK]] |
| - | [[Category: Nara | + | [[Category: Inoue M]] |
| - | [[Category: Sakamoto | + | [[Category: Kita K]] |
| - | [[Category: Shiba | + | [[Category: Lee N]] |
| - | [[Category: Suzuki | + | [[Category: Matsuoka S]] |
| - | [[Category: Tabuchi | + | [[Category: Nara T]] |
| - | [[Category: Tanaka | + | [[Category: Sakamoto K]] |
| - | + | [[Category: Shiba T]] | |
| - | + | [[Category: Suzuki S]] | |
| - | + | [[Category: Tabuchi T]] | |
| - | + | [[Category: Tanaka A]] | |
| - | + | ||
Current revision
Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with NL-2
| |||||||||||
Categories: Large Structures | Trypanosoma cruzi strain CL Brener | Aoki T | Balogun EO | Harada S | Honma T | Iida M | Inaoka DK | Inoue M | Kita K | Lee N | Matsuoka S | Nara T | Sakamoto K | Shiba T | Suzuki S | Tabuchi T | Tanaka A
