This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2qer
From Proteopedia
(Difference between revisions)
| (12 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:2qer.jpg|left|200px]]<br /><applet load="2qer" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2qer, resolution 2.17Å" /> | ||
| - | '''Crystal structure of Cryptosporidium parvum cyclophilin type peptidyl-prolyl cis-trans isomerase cgd2_1660 in the presence of dipeptide ala-pro'''<br /> | ||
| - | == | + | ==Crystal structure of Cryptosporidium parvum cyclophilin type peptidyl-prolyl cis-trans isomerase cgd2_1660 in the presence of dipeptide ala-pro== |
| - | + | <StructureSection load='2qer' size='340' side='right'caption='[[2qer]], [[Resolution|resolution]] 2.17Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | [ | + | <table><tr><td colspan='2'>[[2qer]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryptosporidium_parvum_Iowa_II Cryptosporidium parvum Iowa II]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QER OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QER FirstGlance]. <br> |
| - | [ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.17Å</td></tr> |
| - | [ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ALA:ALANINE'>ALA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PRO:PROLINE'>PRO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | [ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qer FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qer OCA], [https://pdbe.org/2qer PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qer RCSB], [https://www.ebi.ac.uk/pdbsum/2qer PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qer ProSAT]</span></td></tr> |
| - | [ | + | </table> |
| - | [[ | + | == Function == |
| - | + | [https://www.uniprot.org/uniprot/A3FQ68_CRYPI A3FQ68_CRYPI] PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.[RuleBase:RU004223] | |
| - | + | == Evolutionary Conservation == | |
| - | [ | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | [[ | + | Check<jmol> |
| - | [ | + | <jmolCheckbox> |
| - | [[Category: | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qe/2qer_consurf.spt"</scriptWhenChecked> |
| - | [[Category: | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> |
| - | [[Category: | + | <text>to colour the structure by Evolutionary Conservation</text> |
| - | [[Category: | + | </jmolCheckbox> |
| - | [[Category: | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qer ConSurf]. |
| - | [[Category: | + | <div style="clear:both"></div> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Cryptosporidium parvum Iowa II]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Amani M]] |
| - | [[Category: | + | [[Category: Arrowsmith CH]] |
| - | [[Category: | + | [[Category: Artz JD]] |
| - | [[Category: | + | [[Category: Bochkarev A]] |
| - | [[Category: | + | [[Category: Edwards AM]] |
| - | [[Category: | + | [[Category: Hassanali A]] |
| - | [[Category: | + | [[Category: Hills T]] |
| - | [[Category: | + | [[Category: Hui R]] |
| - | [[Category: | + | [[Category: Kozieradzki I]] |
| - | + | [[Category: Lew J]] | |
| - | + | [[Category: Lin L]] | |
| + | [[Category: Schapira M]] | ||
| + | [[Category: Sundstrom M]] | ||
| + | [[Category: Vedadi M]] | ||
| + | [[Category: Wasney G]] | ||
| + | [[Category: Weigelt J]] | ||
| + | [[Category: Wernimont AK]] | ||
| + | [[Category: Zhao Y]] | ||
Current revision
Crystal structure of Cryptosporidium parvum cyclophilin type peptidyl-prolyl cis-trans isomerase cgd2_1660 in the presence of dipeptide ala-pro
| |||||||||||
Categories: Cryptosporidium parvum Iowa II | Large Structures | Amani M | Arrowsmith CH | Artz JD | Bochkarev A | Edwards AM | Hassanali A | Hills T | Hui R | Kozieradzki I | Lew J | Lin L | Schapira M | Sundstrom M | Vedadi M | Wasney G | Weigelt J | Wernimont AK | Zhao Y
