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4c8u

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{{STRUCTURE_4c8u| PDB=4c8u | SCENE= }}
 
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===Xenopus ZNRF3 ectodomain crystal form II===
 
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{{ABSTRACT_PUBMED_24225776}}
 
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==Function==
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==Xenopus ZNRF3 ectodomain crystal form II==
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[[http://www.uniprot.org/uniprot/ZNRF3_XENTR ZNRF3_XENTR]] E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components (By similarity).
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<StructureSection load='4c8u' size='340' side='right'caption='[[4c8u]], [[Resolution|resolution]] 3.01&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4c8u]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Xenopus_tropicalis Xenopus tropicalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C8U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4C8U FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4c8u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c8u OCA], [https://pdbe.org/4c8u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4c8u RCSB], [https://www.ebi.ac.uk/pdbsum/4c8u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4c8u ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[https://www.uniprot.org/uniprot/ZNRF3_XENTR ZNRF3_XENTR]] E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components (By similarity).
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==About this Structure==
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==See Also==
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[[4c8u]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Xenopus_(silurana)_tropicalis Xenopus (silurana) tropicalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C8U OCA].
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*[[Ubiquitin protein ligase 3D structures|Ubiquitin protein ligase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:024225776</ref><references group="xtra"/><references/>
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[[Category: Large Structures]]
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[[Category: Jones, E Y.]]
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[[Category: Xenopus tropicalis]]
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[[Category: Zebisch, M.]]
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[[Category: Jones EY]]
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[[Category: Lgr4]]
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[[Category: Zebisch M]]
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[[Category: Lgr5]]
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[[Category: Lgr6]]
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[[Category: Ligase]]
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[[Category: Membrane]]
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[[Category: R-spo]]
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[[Category: R-spondin]]
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[[Category: Receptor]]
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[[Category: Rnf43]]
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[[Category: Rspo]]
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[[Category: Rspo1]]
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[[Category: Rspo2]]
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[[Category: Rspo3]]
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[[Category: Rspo4]]
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[[Category: Signalling]]
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[[Category: Wnt]]
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Current revision

Xenopus ZNRF3 ectodomain crystal form II

PDB ID 4c8u

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