4fb8
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of apo Acyl-CoA Carboxylase== | |
| - | + | <StructureSection load='4fb8' size='340' side='right'caption='[[4fb8]], [[Resolution|resolution]] 3.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4fb8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FB8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FB8 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3Å</td></tr> | |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fb8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fb8 OCA], [https://pdbe.org/4fb8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fb8 RCSB], [https://www.ebi.ac.uk/pdbsum/4fb8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fb8 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ACCD6_MYCTU ACCD6_MYCTU] Component of a biotin-dependent acyl-CoA carboxylase complex. This subunit transfers the CO2 from carboxybiotin to the CoA ester substrate (PubMed:17114269). When associated with the alpha3 subunit AccA3, is involved in the carboxylation of acetyl-CoA and propionyl-CoA, with a preference for acetyl-CoA (PubMed:17114269).<ref>PMID:17114269</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mycobacterium tuberculosis]] | ||
| + | [[Category: Bruning JB]] | ||
| + | [[Category: Ehrenfeld H]] | ||
| + | [[Category: Reddy MCM]] | ||
| + | [[Category: Sacchettini JC]] | ||
| + | [[Category: Sherekar M]] | ||
| + | [[Category: Valluru S]] | ||
Current revision
Crystal Structure of apo Acyl-CoA Carboxylase
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