4guo

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (15:56, 14 March 2024) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
-
{{STRUCTURE_4guo| PDB=4guo | SCENE= }}
 
-
===structure of p73 DNA binding domain complex with 12 bp DNA===
 
-
==Function==
+
==structure of p73 DNA binding domain complex with 12 bp DNA==
-
[[http://www.uniprot.org/uniprot/P73_HUMAN P73_HUMAN]] Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.<ref>PMID:11753569</ref> <ref>PMID:10203277</ref> <ref>PMID:18174154</ref>
+
<StructureSection load='4guo' size='340' side='right'caption='[[4guo]], [[Resolution|resolution]] 3.19&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[4guo]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GUO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GUO FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.19&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4guo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4guo OCA], [https://pdbe.org/4guo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4guo RCSB], [https://www.ebi.ac.uk/pdbsum/4guo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4guo ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/P73_HUMAN P73_HUMAN] Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.<ref>PMID:11753569</ref> <ref>PMID:10203277</ref> <ref>PMID:18174154</ref>
-
==About this Structure==
+
==See Also==
-
[[4guo]] is a 16 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GUO OCA].
+
*[[P73|P73]]
-
 
+
== References ==
-
==Reference==
+
<references/>
-
<references group="xtra"/><references/>
+
__TOC__
-
[[Category: Ethayathulla, A S]]
+
</StructureSection>
-
[[Category: Viadiu, H.]]
+
[[Category: Homo sapiens]]
-
[[Category: Beta-immunoglobulin fold]]
+
[[Category: Large Structures]]
-
[[Category: Dna]]
+
[[Category: Ethayathulla AS]]
-
[[Category: Dna binding]]
+
[[Category: Viadiu H]]
-
[[Category: Transcription factor]]
+
-
[[Category: Transcription-dna complex]]
+
-
[[Category: Tumor suppressor]]
+

Current revision

structure of p73 DNA binding domain complex with 12 bp DNA

PDB ID 4guo

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4guo"
Personal tools