4i3t

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{{STRUCTURE_4i3t| PDB=4i3t | SCENE= }}
 
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===Structure of phosphonoacetaldehyde dehydrogenase in the apo state===
 
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==About this Structure==
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==Structure of phosphonoacetaldehyde dehydrogenase in the apo state==
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[[4i3t]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I3T OCA].
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<StructureSection load='4i3t' size='340' side='right'caption='[[4i3t]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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[[Category: Agarwal, V.]]
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== Structural highlights ==
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[[Category: Nair, S K.]]
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<table><tr><td colspan='2'>[[4i3t]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Sinorhizobium_meliloti_1021 Sinorhizobium meliloti 1021]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I3T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4I3T FirstGlance]. <br>
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[[Category: Aldehyde dehydrogenase]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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[[Category: Oxidoreductase]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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[[Category: Phosphonate catabolism]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4i3t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i3t OCA], [https://pdbe.org/4i3t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4i3t RCSB], [https://www.ebi.ac.uk/pdbsum/4i3t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4i3t ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PHNY_RHIME PHNY_RHIME] Plays an important role in phosphonate degradation by catalyzing the NAD-dependent conversion of phosphonoacetaldehyde (PnAA) to phosphonoacetate (PnA). Has low in vitro activity with the related compounds phosphonopropionaldehyde (3-oxopropyl phosphonate) and glyceraldehyde 3-phosphate.<ref>PMID:24361046</ref>
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==See Also==
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*[[Aldehyde dehydrogenase 3D structures|Aldehyde dehydrogenase 3D structures]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Sinorhizobium meliloti 1021]]
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[[Category: Agarwal V]]
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[[Category: Nair SK]]

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Structure of phosphonoacetaldehyde dehydrogenase in the apo state

PDB ID 4i3t

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