4lij

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{{STRUCTURE_4lij| PDB=4lij | SCENE= }}
 
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===Crystal structure of a far upstream element (FUSE) binding protein 1 (FUBP1) from Homo sapiens at 1.95 A resolution===
 
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==Function==
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==Crystal structure of a far upstream element (FUSE) binding protein 1 (FUBP1) from Homo sapiens at 1.95 A resolution==
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[[http://www.uniprot.org/uniprot/FUBP1_HUMAN FUBP1_HUMAN]] Regulates MYC expression by binding to a single-stranded far-upstream element (FUSE) upstream of the MYC promoter. May act both as activator and repressor of transcription.<ref>PMID:8125259</ref>
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<StructureSection load='4lij' size='340' side='right'caption='[[4lij]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[4lij]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LIJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LIJ FirstGlance]. <br>
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[[4lij]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LIJ OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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==Reference==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lij FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lij OCA], [https://pdbe.org/4lij PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lij RCSB], [https://www.ebi.ac.uk/pdbsum/4lij PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lij ProSAT]</span></td></tr>
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<references group="xtra"/><references/>
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</table>
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[[Category: Biology, Partnership for T-Cell.]]
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== Function ==
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[[Category: JCSG, Joint Center for Structural Genomics.]]
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[https://www.uniprot.org/uniprot/FUBP1_HUMAN FUBP1_HUMAN] Regulates MYC expression by binding to a single-stranded far-upstream element (FUSE) upstream of the MYC promoter. May act both as activator and repressor of transcription.<ref>PMID:8125259</ref>
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[[Category: TCELL, Partnership for T-Cell Biology.]]
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== References ==
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[[Category: Jcsg]]
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<references/>
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[[Category: Joint center for structural genomic]]
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__TOC__
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[[Category: Kh domain]]
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</StructureSection>
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[[Category: Pf00013]]
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[[Category: Homo sapiens]]
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[[Category: Protein structure initiative]]
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[[Category: Large Structures]]
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[[Category: Psi-biology]]
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[[Category: Partnership for T-Cell Biology]]
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[[Category: Rna-binding protein]]
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[[Category: Structural genomic]]
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Current revision

Crystal structure of a far upstream element (FUSE) binding protein 1 (FUBP1) from Homo sapiens at 1.95 A resolution

PDB ID 4lij

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