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2qvh
From Proteopedia
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| - | [[Image:2qvh.jpg|left|200px]]<br /><applet load="2qvh" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2qvh, resolution 1.76Å" /> | ||
| - | '''Crystal structure of O-succinylbenzoate synthase complexed with O-succinyl benzoate (OSB)'''<br /> | ||
| - | == | + | ==Crystal structure of O-succinylbenzoate synthase complexed with O-succinyl benzoate (OSB)== |
| - | + | <StructureSection load='2qvh' size='340' side='right'caption='[[2qvh]], [[Resolution|resolution]] 1.76Å' scene=''> | |
| - | [ | + | == Structural highlights == |
| - | [ | + | <table><tr><td colspan='2'>[[2qvh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermobifida_fusca_YX Thermobifida fusca YX]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QVH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QVH FirstGlance]. <br> |
| - | [ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.76Å</td></tr> |
| - | [ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=OSB:2-SUCCINYLBENZOATE'>OSB</scene></td></tr> |
| - | [ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qvh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qvh OCA], [https://pdbe.org/2qvh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qvh RCSB], [https://www.ebi.ac.uk/pdbsum/2qvh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qvh ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2qvh TOPSAN]</span></td></tr> |
| - | [ | + | </table> |
| - | + | == Function == | |
| - | [[ | + | [https://www.uniprot.org/uniprot/MENC_THEFY MENC_THEFY] Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB) (PubMed:24060347, PubMed:24872444). Does not show N-succinylamino acid racemase (NSAR) activity with N-succinyl-L-phenylglycine as substrate (PubMed:24872444).<ref>PMID:24060347</ref> <ref>PMID:24872444</ref> |
| - | [ | + | == Evolutionary Conservation == |
| - | [[ | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | [ | + | Check<jmol> |
| - | + | <jmolCheckbox> | |
| - | [[Category: | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qv/2qvh_consurf.spt"</scriptWhenChecked> |
| - | [[Category: | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> |
| - | [[Category: | + | <text>to colour the structure by Evolutionary Conservation</text> |
| - | [[Category: | + | </jmolCheckbox> |
| - | [[Category: | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qvh ConSurf]. |
| - | + | <div style="clear:both"></div> | |
| - | + | == References == | |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Thermobifida fusca YX]] | ||
| + | [[Category: Burley SK]] | ||
| + | [[Category: Sugadev R]] | ||
| + | [[Category: Swaminathan S]] | ||
Current revision
Crystal structure of O-succinylbenzoate synthase complexed with O-succinyl benzoate (OSB)
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