This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4llg

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (12:20, 1 March 2024) (edit) (undo)
 
(3 intermediate revisions not shown.)
Line 1: Line 1:
-
{{STRUCTURE_4llg| PDB=4llg | SCENE= }}
 
-
===Crystal Structure Analysis of the E.coli holoenzyme/Gp2 complex===
 
-
{{ABSTRACT_PUBMED_24218560}}
 
-
==Function==
+
==Crystal Structure Analysis of the E.coli holoenzyme/Gp2 complex==
-
[[http://www.uniprot.org/uniprot/VRPI_BPT7 VRPI_BPT7]] Bacterial RNA polymerase inhibitor, which is expressed in the late stage of lytic development, is also essential for continuous synthesis of phage DNA and functions in the packaging of the viral genome into the mature phage particle. [[http://www.uniprot.org/uniprot/C9QUL2_ECOD1 C9QUL2_ECOD1]] Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity).[HAMAP-Rule:MF_00366][SAAS:SAAS012293_004_017283] [[http://www.uniprot.org/uniprot/C9QXI7_ECOD1 C9QXI7_ECOD1]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity).[HAMAP-Rule:MF_00059] [[http://www.uniprot.org/uniprot/C5A0S8_ECOBW C5A0S8_ECOBW]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity).[SAAS:SAAS012754_004_011999] [[http://www.uniprot.org/uniprot/C9QV90_ECOD1 C9QV90_ECOD1]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity).[HAMAP-Rule:MF_01321][RuleBase:RU000432] [[http://www.uniprot.org/uniprot/RPOD_ECOLI RPOD_ECOLI]] Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This is the primary sigma factor of this bacterium.
+
<StructureSection load='4llg' size='340' side='right'caption='[[4llg]], [[Resolution|resolution]] 3.79&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[4llg]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_BW2952 Escherichia coli BW2952], [https://en.wikipedia.org/wiki/Escherichia_coli_DH1 Escherichia coli DH1], [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12] and [https://en.wikipedia.org/wiki/Escherichia_phage_T7 Escherichia phage T7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LLG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LLG FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.7936&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4llg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4llg OCA], [https://pdbe.org/4llg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4llg RCSB], [https://www.ebi.ac.uk/pdbsum/4llg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4llg ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/RPOD_ECOLI RPOD_ECOLI] Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This is the primary sigma factor of this bacterium.
-
==About this Structure==
+
==See Also==
-
[[4llg]] is a 14 chain structure with sequence from [http://en.wikipedia.org/wiki/Bpt7 Bpt7], [http://en.wikipedia.org/wiki/Ecobw Ecobw], [http://en.wikipedia.org/wiki/Ecod1 Ecod1] and [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LLG OCA].
+
*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
-
 
+
*[[Sigma factor 3D structures|Sigma factor 3D structures]]
-
==Reference==
+
__TOC__
-
<ref group="xtra">PMID:024218560</ref><references group="xtra"/><references/>
+
</StructureSection>
-
[[Category: Bpt7]]
+
[[Category: Escherichia coli BW2952]]
-
[[Category: DNA-directed RNA polymerase]]
+
[[Category: Escherichia coli DH1]]
-
[[Category: Ecobw]]
+
[[Category: Escherichia coli K-12]]
-
[[Category: Ecod1]]
+
[[Category: Escherichia phage T7]]
-
[[Category: Ecoli]]
+
[[Category: Large Structures]]
-
[[Category: Bae, B.]]
+
[[Category: Bae B]]
-
[[Category: Darst, S A.]]
+
[[Category: Darst SA]]
-
[[Category: Transferase]]
+

Current revision

Crystal Structure Analysis of the E.coli holoenzyme/Gp2 complex

PDB ID 4llg

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4llg"
Personal tools