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2r13

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[[Image:2r13.jpg|left|200px]]<br /><applet load="2r13" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="2r13, resolution 1.800&Aring;" />
 
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'''Crystal structure of human mitoNEET reveals a novel [2Fe-2S] cluster coordination'''<br />
 
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==About this Structure==
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==Crystal structure of human mitoNEET reveals a novel [2Fe-2S] cluster coordination==
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2R13 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=CL:'>CL</scene> and <scene name='pdbligand=FES:'>FES</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R13 OCA].
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<StructureSection load='2r13' size='340' side='right'caption='[[2r13]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2r13]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R13 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R13 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r13 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r13 OCA], [https://pdbe.org/2r13 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r13 RCSB], [https://www.ebi.ac.uk/pdbsum/2r13 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r13 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CISD1_HUMAN CISD1_HUMAN] Plays a key role in regulating maximal capacity for electron transport and oxidative phosphorylation (By similarity). May be involved in Fe-S cluster shuttling and/or in redox reactions.<ref>PMID:17584744</ref> <ref>PMID:17766440</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r1/2r13_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2r13 ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Gong, W.]]
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[[Category: Gong W]]
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[[Category: Hou, X.]]
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[[Category: Hou X]]
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[[Category: Liu, R.]]
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[[Category: Liu R]]
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[[Category: Ross, S.]]
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[[Category: Ross S]]
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[[Category: Smart, E J.]]
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[[Category: Smart EJ]]
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[[Category: Zhu, H.]]
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[[Category: Zhu H]]
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[[Category: CL]]
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[[Category: FES]]
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[[Category: acetylation]]
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[[Category: beta-beta-alpha-beta topology]]
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[[Category: metal binding protein]]
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[[Category: metal-binding]]
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[[Category: zinc]]
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[[Category: zinc-finger]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:43:52 2008''
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Current revision

Crystal structure of human mitoNEET reveals a novel [2Fe-2S] cluster coordination

PDB ID 2r13

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