2r13
From Proteopedia
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| - | [[Image:2r13.jpg|left|200px]]<br /><applet load="2r13" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2r13, resolution 1.800Å" /> | ||
| - | '''Crystal structure of human mitoNEET reveals a novel [2Fe-2S] cluster coordination'''<br /> | ||
| - | == | + | ==Crystal structure of human mitoNEET reveals a novel [2Fe-2S] cluster coordination== |
| - | + | <StructureSection load='2r13' size='340' side='right'caption='[[2r13]], [[Resolution|resolution]] 1.80Å' scene=''> | |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2r13]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R13 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R13 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r13 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r13 OCA], [https://pdbe.org/2r13 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r13 RCSB], [https://www.ebi.ac.uk/pdbsum/2r13 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r13 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CISD1_HUMAN CISD1_HUMAN] Plays a key role in regulating maximal capacity for electron transport and oxidative phosphorylation (By similarity). May be involved in Fe-S cluster shuttling and/or in redox reactions.<ref>PMID:17584744</ref> <ref>PMID:17766440</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r1/2r13_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2r13 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Gong | + | [[Category: Gong W]] |
| - | [[Category: Hou | + | [[Category: Hou X]] |
| - | [[Category: Liu | + | [[Category: Liu R]] |
| - | [[Category: Ross | + | [[Category: Ross S]] |
| - | [[Category: Smart | + | [[Category: Smart EJ]] |
| - | [[Category: Zhu | + | [[Category: Zhu H]] |
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Current revision
Crystal structure of human mitoNEET reveals a novel [2Fe-2S] cluster coordination
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Categories: Homo sapiens | Large Structures | Gong W | Hou X | Liu R | Ross S | Smart EJ | Zhu H
