2mho
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Solution State Structure PSD-95 PDZ1 with 5HT2C Receptor peptide== | |
| + | <StructureSection load='2mho' size='340' side='right'caption='[[2mho]]' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2mho]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MHO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MHO FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mho FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mho OCA], [https://pdbe.org/2mho PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mho RCSB], [https://www.ebi.ac.uk/pdbsum/2mho PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mho ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DLG4_RAT DLG4_RAT] Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B.<ref>PMID:15317815</ref> <ref>PMID:15358863</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Postsynaptic density protein 3D structures|Postsynaptic density protein 3D structures]] | |
| - | + | == References == | |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Rattus norvegicus]] | ||
| + | [[Category: Dorr LA]] | ||
| + | [[Category: Lian L]] | ||
| + | [[Category: Phelan MM]] | ||
Current revision
Solution State Structure PSD-95 PDZ1 with 5HT2C Receptor peptide
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