4chc
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4chc is ON HOLD Authors: Guilligay, D., Kadlec, J., Crepin, T., Lunardi, T., Bouvier, D., Kochs, G., Ruigrok, R.W.H., Cusack, S. Description: Cryst...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the N-terminal domain of the PA subunit of Thogoto virus polymerase (form 2)== | |
| + | <StructureSection load='4chc' size='340' side='right'caption='[[4chc]], [[Resolution|resolution]] 2.77Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4chc]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Thogoto_thogotovirus Thogoto thogotovirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CHC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CHC FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.77Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4chc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4chc OCA], [https://pdbe.org/4chc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4chc RCSB], [https://www.ebi.ac.uk/pdbsum/4chc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4chc ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PA_THOGV PA_THOGV] Initiates transcription by a unique cap-stealing mechanism that involves the cleavage of only the m(7)GpppAm structure from cellular hnRNAs. | ||
| - | + | ==See Also== | |
| - | + | *[[RNA polymerase 3D structures|RNA polymerase 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Thogoto thogotovirus]] | ||
| + | [[Category: Bouvier D]] | ||
| + | [[Category: Crepin T]] | ||
| + | [[Category: Cusack S]] | ||
| + | [[Category: Guilligay D]] | ||
| + | [[Category: Kadlec J]] | ||
| + | [[Category: Kochs G]] | ||
| + | [[Category: Lunardi T]] | ||
| + | [[Category: Ruigrok RWH]] | ||
Current revision
Crystal structure of the N-terminal domain of the PA subunit of Thogoto virus polymerase (form 2)
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