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4chg
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of VapBC15 complex from Mycobacterium tuberculosis== | |
| - | + | <StructureSection load='4chg' size='340' side='right'caption='[[4chg]], [[Resolution|resolution]] 2.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4chg]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CHG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CHG FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4chg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4chg OCA], [https://pdbe.org/4chg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4chg RCSB], [https://www.ebi.ac.uk/pdbsum/4chg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4chg ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/VPC15_MYCTU VPC15_MYCTU]] Toxic component of a toxin-antitoxin (TA) module. An RNase (By similarity). Upon expression in M.smegmatis inhibits colony formation. Its toxic effect is neutralized by coexpression with cognate antitoxin VapB15.[HAMAP-Rule:MF_00265]<ref>PMID:20011113</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mycobacterium tuberculosis H37Rv]] | ||
| + | [[Category: Das U]] | ||
| + | [[Category: Gourinath S]] | ||
| + | [[Category: Pogenberg V]] | ||
| + | [[Category: Srinivasan A]] | ||
| + | [[Category: Tiruttani Subhramanyam UK]] | ||
| + | [[Category: Wilmanns M]] | ||
Current revision
Crystal structure of VapBC15 complex from Mycobacterium tuberculosis
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