4lil

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{{STRUCTURE_4lil| PDB=4lil | SCENE= }}
 
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===Crystal structure of the catalytic subunit of human primase bound to UTP and Mn===
 
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{{ABSTRACT_PUBMED_24239947}}
 
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==Function==
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==Crystal structure of the catalytic subunit of human primase bound to UTP and Mn==
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[[http://www.uniprot.org/uniprot/PRI1_HUMAN PRI1_HUMAN]] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.
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<StructureSection load='4lil' size='340' side='right'caption='[[4lil]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4lil]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LIL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LIL FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=UTP:URIDINE+5-TRIPHOSPHATE'>UTP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lil FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lil OCA], [https://pdbe.org/4lil PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lil RCSB], [https://www.ebi.ac.uk/pdbsum/4lil PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lil ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PRI1_HUMAN PRI1_HUMAN] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.
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==About this Structure==
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==See Also==
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[[4lil]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LIL OCA].
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*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:024239947</ref><references group="xtra"/><references/>
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[[Category: Homo sapiens]]
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[[Category: Chazin, W J.]]
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[[Category: Large Structures]]
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[[Category: Eichman, B F.]]
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[[Category: Chazin WJ]]
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[[Category: Vaithiyalingam, S.]]
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[[Category: Eichman BF]]
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[[Category: Prim fold]]
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[[Category: Vaithiyalingam S]]
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[[Category: Transferase]]
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Current revision

Crystal structure of the catalytic subunit of human primase bound to UTP and Mn

PDB ID 4lil

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