4hec
From Proteopedia
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| - | {{STRUCTURE_4hec|  PDB=4hec  |  SCENE=  }}  | ||
| - | ===Crystal structure of a putative uncharacterized protein from Mycobacterium tuberculosis=== | ||
| - | {{ABSTRACT_PUBMED_24311791}} | ||
| - | == | + | ==Crystal structure of a putative uncharacterized protein from Mycobacterium tuberculosis== | 
| - | [[4hec]] is a 2 chain structure with sequence from [ | + | <StructureSection load='4hec' size='340' side='right'caption='[[4hec]], [[Resolution|resolution]] 1.80Å' scene=''> | 
| - | + | == Structural highlights == | |
| - | == | + | <table><tr><td colspan='2'>[[4hec]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HEC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HEC FirstGlance]. <br> | 
| - | < | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | 
| - | [[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | 
| - | [ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hec FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hec OCA], [https://pdbe.org/4hec PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hec RCSB], [https://www.ebi.ac.uk/pdbsum/4hec PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hec ProSAT]</span></td></tr> | 
| - | [ | + | </table> | 
| - | + | == Function == | |
| - | [ | + | [https://www.uniprot.org/uniprot/EXRBN_MYCTU EXRBN_MYCTU] Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA. Has no activity with 5' overhangs. Has negligible endonuclease activity. Can bind ATP, dATP and AMP (in vitro); the nucleotide occupies the predicted substrate binding site.<ref>PMID:24311791</ref>  | 
| - | [[Category:  | + | == References == | 
| - | [[Category:  | + | <references/> | 
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mycobacterium tuberculosis H37Rv]] | ||
Current revision
Crystal structure of a putative uncharacterized protein from Mycobacterium tuberculosis
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