4n2o

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{{STRUCTURE_4n2o| PDB=4n2o | SCENE= }}
 
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===Structure of a novel autonomous cohesin protein from Ruminococcus flavefaciens===
 
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==About this Structure==
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==Structure of a novel autonomous cohesin protein from Ruminococcus flavefaciens==
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[[4n2o]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N2O OCA].
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<StructureSection load='4n2o' size='340' side='right'caption='[[4n2o]], [[Resolution|resolution]] 2.44&Aring;' scene=''>
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[[Category: Bayer, E.]]
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== Structural highlights ==
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[[Category: Frolow, F.]]
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<table><tr><td colspan='2'>[[4n2o]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Ruminococcus_flavefaciens Ruminococcus flavefaciens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N2O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4N2O FirstGlance]. <br>
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[[Category: Lamed, R.]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.442&#8491;</td></tr>
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[[Category: Levy-Assaraf, M.]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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[[Category: Shimon, L.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4n2o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n2o OCA], [https://pdbe.org/4n2o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4n2o RCSB], [https://www.ebi.ac.uk/pdbsum/4n2o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4n2o ProSAT]</span></td></tr>
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[[Category: Voronov-Goldman, M.]]
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</table>
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[[Category: Cohesin]]
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== Function ==
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[[Category: Dockerin]]
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[https://www.uniprot.org/uniprot/W5IDC3_RUMFL W5IDC3_RUMFL]
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[[Category: Nine-stranded beta sandwich]]
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<div style="background-color:#fffaf0;">
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[[Category: Structural protein]]
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== Publication Abstract from PubMed ==
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Ruminococcus flavefaciens is a cellulolytic bacterium found in the rumen of herbivores and produces one of the most elaborate and variable cellulosome systems. The structure of an R. flavefaciens protein (RfCohG, ZP_06142108), representing a freestanding (non-cellulosomal) type III cohesin module, has been determined. A selenomethionine derivative with a C-terminal histidine tag was crystallized and diffraction data were measured to 2.44 A resolution. Its structure was determined by single-wavelength anomalous dispersion, revealing eight molecules in the asymmetric unit. RfCohG exhibits the most complex among all known cohesin structures, possessing four alpha-helical elements and a topographical protuberance on the putative dockerin-binding surface.
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Structural characterization of a novel autonomous cohesin from Ruminococcus flavefaciens.,Voronov-Goldman M, Levy-Assaraf M, Yaniv O, Wisserman G, Jindou S, Borovok I, Bayer EA, Lamed R, Shimon LJ, Frolow F Acta Crystallogr F Struct Biol Commun. 2014 Apr;70(Pt 4):450-6. doi:, 10.1107/S2053230X14004051. Epub 2014 Mar 25. PMID:24699736<ref>PMID:24699736</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 4n2o" style="background-color:#fffaf0;"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Ruminococcus flavefaciens]]
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[[Category: Bayer E]]
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[[Category: Frolow F]]
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[[Category: Lamed R]]
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[[Category: Levy-Assaraf M]]
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[[Category: Shimon L]]
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[[Category: Voronov-Goldman M]]

Current revision

Structure of a novel autonomous cohesin protein from Ruminococcus flavefaciens

PDB ID 4n2o

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