4nqn

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{{STRUCTURE_4nqn| PDB=4nqn | SCENE= }}
 
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===Crystal Structure of the bromodomain of human BRD9 in complex with a triazolo-phthalazine ligand===
 
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==About this Structure==
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==Crystal Structure of the bromodomain of human BRD9 in complex with a triazolo-phthalazine ligand==
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[[4nqn]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NQN OCA].
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<StructureSection load='4nqn' size='340' side='right'caption='[[4nqn]], [[Resolution|resolution]] 1.73&Aring;' scene=''>
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[[Category: Arrowsmith, C H.]]
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== Structural highlights ==
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[[Category: Bountra, C.]]
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<table><tr><td colspan='2'>[[4nqn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NQN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NQN FirstGlance]. <br>
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[[Category: Delft, F von.]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.73&#8491;</td></tr>
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[[Category: Edwards, A M.]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=Y1Z:2-CHLORO-N-[5-(3-METHYL[1,2,4]TRIAZOLO[3,4-A]PHTHALAZIN-6-YL)-2-(MORPHOLIN-4-YL)PHENYL]BENZENESULFONAMIDE'>Y1Z</scene></td></tr>
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[[Category: Fedorov, O.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nqn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nqn OCA], [https://pdbe.org/4nqn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nqn RCSB], [https://www.ebi.ac.uk/pdbsum/4nqn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nqn ProSAT]</span></td></tr>
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[[Category: Felletar, I.]]
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</table>
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[[Category: Filippakopoulos, P.]]
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== Function ==
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[[Category: Knapp, S.]]
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[https://www.uniprot.org/uniprot/BRD9_HUMAN BRD9_HUMAN] May play a role in chromatin remodeling and regulation of transcription.
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[[Category: Martin, S.]]
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[[Category: Picaud, S.]]
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==See Also==
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[[Category: SGC, Structural Genomics Consortium.]]
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*[[Bromodomain-containing protein 3D structures|Bromodomain-containing protein 3D structures]]
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[[Category: Bromodomain]]
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__TOC__
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[[Category: Inhibition]]
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</StructureSection>
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[[Category: Sgc]]
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[[Category: Homo sapiens]]
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[[Category: Small molecule inhibitor]]
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[[Category: Large Structures]]
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[[Category: Structural genomics consortium]]
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[[Category: Arrowsmith CH]]
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[[Category: Transcription]]
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[[Category: Bountra C]]
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[[Category: Transcription-inhibitor complex]]
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[[Category: Edwards AM]]
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[[Category: Fedorov O]]
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[[Category: Felletar I]]
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[[Category: Filippakopoulos P]]
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[[Category: Knapp S]]
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[[Category: Martin S]]
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[[Category: Picaud S]]
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[[Category: Von Delft F]]

Current revision

Crystal Structure of the bromodomain of human BRD9 in complex with a triazolo-phthalazine ligand

PDB ID 4nqn

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