4f3v

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{{STRUCTURE_4f3v| PDB=4f3v | SCENE= }}
 
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===Crystal structure of N-terminal domain of EccA1 ATPase from ESX-1 secretion system of Mycobacterium tuberculosis===
 
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{{ABSTRACT_PUBMED_23818233}}
 
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==Function==
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==Crystal structure of N-terminal domain of EccA1 ATPase from ESX-1 secretion system of Mycobacterium tuberculosis==
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[[http://www.uniprot.org/uniprot/ECCA1_MYCTU ECCA1_MYCTU]] Probably part of a complex that is involved in secretion of ESX-1 substrates, such as EsxA (ESAT-6) and EsxB (CFP-10). Shows ATPase activity. Could provide energy for export of ESX-1 substrates.<ref>PMID:18974091</ref> <ref>PMID:16368961</ref>
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<StructureSection load='4f3v' size='340' side='right'caption='[[4f3v]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[4f3v]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F3V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4F3V FirstGlance]. <br>
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[[4f3v]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F3V OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SM:SAMARIUM+(III)+ION'>SM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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==Reference==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4f3v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f3v OCA], [https://pdbe.org/4f3v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4f3v RCSB], [https://www.ebi.ac.uk/pdbsum/4f3v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4f3v ProSAT]</span></td></tr>
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<ref group="xtra">PMID:023818233</ref><references group="xtra"/><references/>
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</table>
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[[Category: Evans, T J.]]
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== Function ==
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[[Category: Korotkov, K V.]]
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[https://www.uniprot.org/uniprot/ECCA1_MYCTU ECCA1_MYCTU] Probably part of a complex that is involved in secretion of ESX-1 substrates, such as EsxA (ESAT-6) and EsxB (CFP-10). Shows ATPase activity. Could provide energy for export of ESX-1 substrates.<ref>PMID:18974091</ref> <ref>PMID:16368961</ref>
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[[Category: Atpase]]
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== References ==
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[[Category: Protein secretion]]
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<references/>
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[[Category: Protein transport]]
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__TOC__
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[[Category: Tetratricopeptide repeat]]
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</StructureSection>
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[[Category: Tpr domain]]
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[[Category: Large Structures]]
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Evans TJ]]
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[[Category: Korotkov KV]]

Current revision

Crystal structure of N-terminal domain of EccA1 ATPase from ESX-1 secretion system of Mycobacterium tuberculosis

PDB ID 4f3v

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