4nl5
From Proteopedia
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- | '''Unreleased structure''' | ||
- | + | ==Mycobacterium tuberculosis heme-degrading protein MhuD in complex with heme and cyanide== | |
+ | <StructureSection load='4nl5' size='340' side='right'caption='[[4nl5]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
+ | == Structural highlights == | ||
+ | <table><tr><td colspan='2'>[[4nl5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NL5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NL5 FirstGlance]. <br> | ||
+ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | ||
+ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CYN:CYANIDE+ION'>CYN</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr> | ||
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nl5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nl5 OCA], [https://pdbe.org/4nl5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nl5 RCSB], [https://www.ebi.ac.uk/pdbsum/4nl5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nl5 ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/MHUD_MYCTU MHUD_MYCTU] Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron. | ||
- | + | ==See Also== | |
- | + | *[[Monooxygenase 3D structures|Monooxygenase 3D structures]] | |
- | + | __TOC__ | |
+ | </StructureSection> | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Mycobacterium tuberculosis]] | ||
+ | [[Category: Chao A]] | ||
+ | [[Category: Goulding CW]] | ||
+ | [[Category: Morse RP]] |
Current revision
Mycobacterium tuberculosis heme-degrading protein MhuD in complex with heme and cyanide
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