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4fra
From Proteopedia
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| - | {{STRUCTURE_4fra| PDB=4fra | SCENE= }} | ||
| - | ===Crystal Structure of ABBA+UDP+Gal at pH 5.0 with MPD as the cryoprotectant=== | ||
| - | {{ABSTRACT_PUBMED_24265507}} | ||
| - | == | + | ==Crystal Structure of ABBA+UDP+Gal at pH 5.0 with MPD as the cryoprotectant== |
| - | [[4fra]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FRA OCA]. | + | <StructureSection load='4fra' size='340' side='right'caption='[[4fra]], [[Resolution|resolution]] 1.43Å' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4fra]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FRA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FRA FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.43Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fra FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fra OCA], [https://pdbe.org/4fra PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fra RCSB], [https://www.ebi.ac.uk/pdbsum/4fra PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fra ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/BGAT_HUMAN BGAT_HUMAN] This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity. | ||
| - | == | + | ==See Also== |
| - | + | *[[Glycosyltransferase 3D structures|Glycosyltransferase 3D structures]] | |
| - | [[ | + | __TOC__ |
| - | + | </StructureSection> | |
| - | + | [[Category: Homo sapiens]] | |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Alfaro JA]] |
| - | [[Category: | + | [[Category: Blackler RJ]] |
| - | [[Category: | + | [[Category: Borisova SN]] |
| - | [[Category: | + | [[Category: Evans SV]] |
| - | [[Category: | + | [[Category: Johal AR]] |
| - | [[Category: | + | [[Category: Schuman B]] |
| - | [[Category: | + | |
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Current revision
Crystal Structure of ABBA+UDP+Gal at pH 5.0 with MPD as the cryoprotectant
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